» Articles » PMID: 26031963

Eliminating Infections in the ICU: CLABSI

Overview
Date 2015 Jun 3
PMID 26031963
Citations 11
Authors
Affiliations
Soon will be listed here.
Abstract

Central line-associated bloodstream infections (CLABSI) are one of the leading causes of death in the USA and around the world. As a preventable healthcare-associated infection, they are associated with significant morbidity and excess costs to the healthcare system. Effective and long-term CLABSI prevention requires a multifaceted approach, involving evidence-based best practices coupled with effective implementation strategies. Currently recommended practices are supported by evidence and are simple, such as appropriate hand hygiene, use of full barrier precautions, avoidance of femoral lines, skin antisepsis, and removal of unnecessary lines. The most successful and sustained improvements in CLABSI rates further utilize an adaptive component to align provider behaviors with consistent and reliable use of evidence-based practices. Great success has been achieved in reducing CLABSI rates in the USA and elsewhere over the past decade, but more is needed. This article aims to review the initiatives undertaken to reduce CLABSI and summarizes the sentinel and recent literature regarding CLABSI and its prevention.

Citing Articles

Incidence Rate, Pathogens and Economic Burden of Catheter-Related Bloodstream Infection: A Single-Center, Retrospective Case-Control Study.

Zhang Y, Wang Y, Sheng Z, Wang Q, Shi D, Xu S Infect Drug Resist. 2023; 16:3551-3560.

PMID: 37305736 PMC: 10256568. DOI: 10.2147/IDR.S406681.


[Chlorhexidine bathing in intensive care units for the prevention of nosocomial infections. A systematic review].

Esarte J, Mujika A An Sist Sanit Navar. 2022; 45(3).

PMID: 36576389 PMC: 10065041. DOI: 10.23938/ASSN.1027.


Dynamic Monitoring of Systemic Biomarkers with Gastric Sensors.

Steiger C, Phan N, Huang H, Sun H, Chu J, Reker D Adv Sci (Weinh). 2021; 8(24):e2102861.

PMID: 34713599 PMC: 8693042. DOI: 10.1002/advs.202102861.


Improving clinical outcomes of very low birth weight infants: Implementation of standardized management guidelines in tertiary care hospital in Haryana.

Arora S, Yadav P, Bajaj H, Thakur A, Mittal M, Gupta M Int J Pediatr Adolesc Med. 2020; 7(4):174-180.

PMID: 33319015 PMC: 7729219. DOI: 10.1016/j.ijpam.2019.08.002.


Deconstruction of central line insertion guidelines based on the positive deviance approach-Reducing gaps between guidelines and implementation: A qualitative ethnographic research.

Cohen R, Gesser-Edelsburg A, Singhal A, Benenson S, Moses A PLoS One. 2019; 14(9):e0222608.

PMID: 31536568 PMC: 6752780. DOI: 10.1371/journal.pone.0222608.


References
1.
Waters H, Korn Jr R, Colantuoni E, Berenholtz S, Goeschel C, Needham D . The business case for quality: economic analysis of the Michigan Keystone Patient Safety Program in ICUs. Am J Med Qual. 2011; 26(5):333-9. DOI: 10.1177/1062860611410685. View

2.
Goudie A, Dynan L, Brady P, Rettiganti M . Attributable cost and length of stay for central line-associated bloodstream infections. Pediatrics. 2014; 133(6):e1525-32. PMC: 4258643. DOI: 10.1542/peds.2013-3795. View

3.
Pronovost P . Interventions to decrease catheter-related bloodstream infections in the ICU: the Keystone Intensive Care Unit Project. Am J Infect Control. 2008; 36(10):S171.e1-5. DOI: 10.1016/j.ajic.2008.10.008. View

4.
Paglialonga F, Consolo S, Biasuzzi A, Assomou J, Gattarello E, Patricelli M . Reduction in catheter-related infections after switching from povidone-iodine to chlorhexidine for the exit-site care of tunneled central venous catheters in children on hemodialysis. Hemodial Int. 2014; 18 Suppl 1:S13-8. DOI: 10.1111/hdi.12218. View

5.
Dixon-Woods M, Leslie M, Bion J, Tarrant C . What counts? An ethnographic study of infection data reported to a patient safety program. Milbank Q. 2012; 90(3):548-91. PMC: 3479383. DOI: 10.1111/j.1468-0009.2012.00674.x. View