Lhermitte's Sign: The Current Status

Overview

Journal Ann Indian Acad Neurol

Specialty Neurology

Date 2015 May 29

PMID 26019410

Citations 10

Authors

Supreet Khare

Deeksha Seth

Affiliations

Soon will be listed here.

Abstract

Lhermitte's sign was described by Marie and Chatelin and named after Jean Lhermitte. This sign is mostly described as an electric shock like condition by some patients of multiple sclerosis. This sensation occurs when the neck is moved in a wrong way or rather flexed. It can also travel down to the spine, arms, and legs, and sometimes the trunk. Demyelination and hyperexcitability are the main pathophysiological reasons depicted for the Lhermitte's sign. Other causes for Lhermitte's sign include transverse myelitis, behçet's disease, trauma, etc. This article reviews the Lhermitte's sign, its history, and its etiopathophysiology. Very few studies are available on Lermitte's sign and more research need to be done on the same to ensure its sensitivity and specificity.

Citing Articles

An Uncommon Presentation of Guillain-Barré Syndrome With Lhermitte Sign.

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Lhermitte's Sign--A Neuropathic Pain and Its Neuroanatomy.

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Neuropathic Pain in Multiple Sclerosis and Its Animal Models: Focus on Mechanisms, Knowledge Gaps and Future Directions.

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