The Metabolic Syndrome and Associated Lifestyle Factors Among the Iranian Population

Overview

Journal Adv Biomed Res

Specialty Biomedical Engineering

Date 2015 May 28

PMID 26015910

Citations 7

Authors

Mojgan Gharipour

Nizal Sarrafzadegan

Masoumeh Sadeghi

Alireza Khosravi

Mohsen Hoseini

Hossein Khosravi-Boroujeni

Arsalan Khaledifar

Affiliations

Soon will be listed here.

Abstract

Background: This study aims to evaluate the impact of the Isfahan Healthy Heart Program (IHHP) interventions concerning healthy behavior, on the prevalence of the metabolic syndrome (MetS) and its components in the Iranian population.

Materials And Methods: The IHHP targeted the population at large in three districts in central Iran from 2000 to 2007. Numerous interventional activities were performed to improve lifestyle. The main intervention strategies were public education through mass media, intersectional cooperation, health professional education, marketing and organizational development, legislation and policy development, as well as research and evaluation. MetS was defined based on the Adult Treatment Panel (ATP) III definition. The logistic regression method was applied to explore the relationship between lifestyle factors with components of metabolic risk factors.

Results: The mean age of the participants was 44.68 ± 14.43 years in 2001. The mean values of the MetS components differed from 2001 to 2007. The mean of systolic blood pressure (SBP) decreased from 126.7 ± 22.31 to 124.21 ± 20.0 and from 129.47 ± 23.08 to 126.26 ± 21.88 among females in both the intervention and reference areas. Similar changes were observed among males. The mean diastolic blood pressure (DBP) and triglycerides decreased significantly in the intervention area and increased significantly in the reference area in both sexes. High density protein cholesterol (HDL-C) was decreased in both sexes, from 2001 to 2007, in both areas. A strong relationship between tobacco control with high SBP and hypertriglyceridemia was found (P < 0.01).

Conclusion: Lifestyle improvement programs could be useful to improve the MetS status among men and women.

Citing Articles

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Gaffari-Fam S, Babazadeh T, Oliaei S, Behboodi L, Daemi A Patient Prefer Adherence. 2020; 14:499-506.

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The association between the serum 25-hydroxyvitamin D level and cardiovascular events in individuals with and without metabolic syndrome.

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References

Baghaei A, Sarrafzadegan N, Rabiei K, Gharipour M, Tavasoli A, Shirani S . How effective are strategies for non-communicable disease prevention and control in a high risk population in a developing country? Isfahan Healthy Heart Programme. Arch Med Sci. 2012; 6(1):24-31. PMC: 3278939. DOI: 10.5114/aoms.2010.13503. View

Tavassoli A, Gharipour M, Khosravi A, Kelishadi R, Siadat Z, Bahonar A . Gender differences in obesogenic behaviour, socioeconomic and metabolic factors in a population-based sample of Iranians: the IHHP study. J Health Popul Nutr. 2011; 28(6):602-9. PMC: 2995029. DOI: 10.3329/jhpn.v28i6.6609. View

Sarrafzadegan N, Kelishadi R, Esmaillzadeh A, Mohammadifard N, Rabiei K, Roohafza H . Do lifestyle interventions work in developing countries? Findings from the Isfahan Healthy Heart Program in the Islamic Republic of Iran. Bull World Health Organ. 2009; 87(1):39-50. PMC: 2649597. DOI: 10.2471/blt.07.049841. View

Moran L, Hutchison S, Norman R, Teede H . Lifestyle changes in women with polycystic ovary syndrome. Cochrane Database Syst Rev. 2011; (2):CD007506. DOI: 10.1002/14651858.CD007506.pub2. View

Sarraf-Zadegan N, Sayed-Tabatabaei F, Bashardoost N, Maleki A, Totonchi M, Habibi H . The prevalence of coronary artery disease in an urban population in Isfahan, Iran. Acta Cardiol. 1999; 54(5):257-63. View

Mohammadifard N, Kelishadi R, Safavi M, Sarrafzadegan N, Sajadi F, Sadri G . Effect of a community-based intervention on nutritional behaviour in a developing country setting: the Isfahan Healthy Heart Programme. Public Health Nutr. 2009; 12(9):1422-30. DOI: 10.1017/S1368980008004230. View

Ebrahim S, Beswick A, Burke M, Davey Smith G . Multiple risk factor interventions for primary prevention of coronary heart disease. Cochrane Database Syst Rev. 2006; (4):CD001561. PMC: 4160097. DOI: 10.1002/14651858.CD001561.pub2. View

Gulseth H, Gjelstad I, Tierney A, Shaw D, Helal O, Hees A . Dietary fat modifications and blood pressure in subjects with the metabolic syndrome in the LIPGENE dietary intervention study. Br J Nutr. 2010; 104(2):160-3. DOI: 10.1017/S0007114510000565. View

Pelikanova T . [Treatment of diabetes in metabolic syndrome]. Vnitr Lek. 2009; 55(7-8):637-45. View

10.

Cornier M, Dabelea D, Hernandez T, Lindstrom R, Steig A, Stob N . The metabolic syndrome. Endocr Rev. 2008; 29(7):777-822. PMC: 5393149. DOI: 10.1210/er.2008-0024. View

11.

Panagiotakos D, Pitsavos C, Chrysohoou C, Skoumas J, Tousoulis D, Toutouza M . Impact of lifestyle habits on the prevalence of the metabolic syndrome among Greek adults from the ATTICA study. Am Heart J. 2003; 147(1):106-12. DOI: 10.1016/s0002-8703(03)00442-3. View

12.

Ilanne-Parikka P, Laaksonen D, Eriksson J, Lakka T, Lindstr J, Peltonen M . Leisure-time physical activity and the metabolic syndrome in the Finnish diabetes prevention study. Diabetes Care. 2010; 33(7):1610-7. PMC: 2890369. DOI: 10.2337/dc09-2155. View

13.

Gharipour M, Sarrafzadegan N, Sadeghi M, Andalib E, Talaie M, Shafie D . Predictors of metabolic syndrome in the Iranian population: waist circumference, body mass index, or waist to hip ratio?. Cholesterol. 2013; 2013:198384. PMC: 3619538. DOI: 10.1155/2013/198384. View

14.

. Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III). JAMA. 2001; 285(19):2486-97. DOI: 10.1001/jama.285.19.2486. View

15.

Gharipour M, Kelishadi R, Khosravi A, Shirani S, Masjedi M, Sarrafzadegan N . The impact of a community trial on the pharmacological treatment in the individuals with the metabolic syndrome: findings from the Isfahan Healthy Heart Program, 2001-2007. Arch Med Sci. 2013; 8(6):1009-17. PMC: 3542491. DOI: 10.5114/aoms.2012.32407. View

16.

Miyatake N, Fujii M, Miyachi M, Tabata I, Takeshi S, Hirao T . Changes in metabolic syndrome and its components with lifestyle modification in Japanese men. Intern Med. 2010; 49(4):261-5. DOI: 10.2169/internalmedicine.49.2900. View

17.

Wagh A, Stone N . Treatment of metabolic syndrome. Expert Rev Cardiovasc Ther. 2004; 2(2):213-28. DOI: 10.1586/14779072.2.2.213. View

18.

Kirkendoll K, Clark P, Grossniklaus D, Igho-Pemu P, Mullis R, Dunbar S . Metabolic syndrome in African Americans: views on making lifestyle changes. J Transcult Nurs. 2010; 21(2):104-13. PMC: 2838196. DOI: 10.1177/1043659609357636. View

19.

Giri M . Medical management of obesity. Acta Clin Belg. 2007; 61(5):286-94. DOI: 10.1179/acb.2006.048. View

20.

Sarrafzadegan N, Azadbakht L, Mohammadifard N, Esmaillzadeh A, Safavi M, Sajadi F . Do lifestyle interventions affect dietary diversity score in the general population?. Public Health Nutr. 2009; 12(10):1924-30. DOI: 10.1017/S1368980009004856. View