Dietary Intake and Phthalates Body Burden in Boys and Girls

Overview

Journal Arch Public Health

Publisher Biomed Central

Date 2015 May 15

PMID 25973195

Citations 10

Authors

Qing Shen

Huijing Shi

Yunhui Zhang

Yang Cao

Affiliations

Soon will be listed here.

Abstract

Background: Phthalates are a group of environmental endocrine disruptors and have been ubiquitously applied in industrial field. Few studies had investigated how dietary intake was related with phthalate body burden in children. To determine the relationship between phthalate body burden and dietary intake among school age children in Shanghai, China.

Methods: Four hundred and thirty schoolchildren aged 8-16 years were recruited in a cross-sectional study with 18 months follow-up in Shanghai, China during 2010-2012. Data of questionnaire-based dietary intake were collected and urinary phthalate concentrations were measured. Associations between frequency of dietary intake and phthalate metabolite concentrations were evaluated by stepwise multiple linear regression model.

Results: Positive association was found between mono-butyl phthalate and seafood, and negative associations were found between mono-butyl phthalate and dried fruits and vegetables. Egg consumption showed negative association with all di-(2-ethylhexyl) phthalate-related metabolites.

Conclusions: Some food types were identified to be associated with phthalate body burden and diet might be a source of phthalate exposure among Chinese schoolchildren.

Citing Articles

Plastics in human diets: development and evaluation of the 24-h Dietary Recall - Plastic Exposure and the Dietary Plastics Score.

Harray A, Herrmann S, Papendorf H, Miller C, Vermeersch A, Smith T Front Nutr. 2024; 11:1443792.

PMID: 39360279 PMC: 11444960. DOI: 10.3389/fnut.2024.1443792.

Effects of di-(2-ethylhexyl) phthalate on growth, metabolism, and virulence of the plant pathogenic bacterium .

Kim Y, Sang M Front Cell Infect Microbiol. 2023; 13:1228713.

PMID: 37692166 PMC: 10485622. DOI: 10.3389/fcimb.2023.1228713.

Prenatal Exposure to Di-Ethyl Phthalate (DEP) Is Related to Increasing Neonatal IgE Levels and the Altering of the Immune Polarization of Helper-T Cells.

Tsai C, Cheng H, Hsu T, Wang J, Hung C, Tsai C Int J Environ Res Public Health. 2021; 18(12).

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Distribution and Dietary Predictors of Urinary Phthalate Metabolites among Pregnant Women in Shanghai, China.

He X, Zang J, Liao P, Zheng Y, Lu Y, Zhu Z Int J Environ Res Public Health. 2019; 16(8).

PMID: 30995748 PMC: 6518169. DOI: 10.3390/ijerph16081366.

A Review of Biomonitoring of Phthalate Exposures.

Wang Y, Zhu H, Kannan K Toxics. 2019; 7(2).

PMID: 30959800 PMC: 6630674. DOI: 10.3390/toxics7020021.

References

Martine B, Marie-Jeanne T, Cendrine D, Fabrice A, Marc C . Assessment of adult human exposure to phthalate esters in the urban centre of Paris (France). Bull Environ Contam Toxicol. 2012; 90(1):91-6. DOI: 10.1007/s00128-012-0859-5. View

Tsumura Y, Ishimitsu S, Saito I, Sakai H, Kobayashi Y, Tonogai Y . Eleven phthalate esters and di(2-ethylhexyl) adipate in one-week duplicate diet samples obtained from hospitals and their estimated daily intake. Food Addit Contam. 2001; 18(5):449-60. DOI: 10.1080/02652030117484. View

Bornehag C, Nanberg E . Phthalate exposure and asthma in children. Int J Androl. 2010; 33(2):333-45. DOI: 10.1111/j.1365-2605.2009.01023.x. View

Guart A, Bono-Blay F, Borrell A, Lacorte S . Migration of plasticizers phthalates, bisphenol A and alkylphenols from plastic containers and evaluation of risk. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2011; 28(5):676-85. DOI: 10.1080/19440049.2011.555845. View

Schettler T . Human exposure to phthalates via consumer products. Int J Androl. 2006; 29(1):134-9. DOI: 10.1111/j.1365-2605.2005.00567.x. View

Cirillo T, Fasano E, Castaldi E, Montuori P, Cocchieri R . Children's exposure to Di(2-ethylhexyl)phthalate and dibutylphthalate plasticizers from school meals. J Agric Food Chem. 2011; 59(19):10532-8. DOI: 10.1021/jf2020446. View

Fromme H, Gruber L, Schlummer M, Wolz G, Bohmer S, Angerer J . Intake of phthalates and di(2-ethylhexyl)adipate: results of the Integrated Exposure Assessment Survey based on duplicate diet samples and biomonitoring data. Environ Int. 2007; 33(8):1012-20. DOI: 10.1016/j.envint.2007.05.006. View

Yum T, Lee S, Kim Y . Association between precocious puberty and some endocrine disruptors in human plasma. J Environ Sci Health A Tox Hazard Subst Environ Eng. 2013; 48(8):912-7. DOI: 10.1080/10934529.2013.762734. View

Li Y, He Y, Zhai F, Yang X, Hu X, Zhao W . [Comparison of assessment of food intakes by using 3 dietary survey methods]. Zhonghua Yu Fang Yi Xue Za Zhi. 2006; 40(4):273-80. View

10.

Hauser R, Meeker J, Park S, Silva M, Calafat A . Temporal variability of urinary phthalate metabolite levels in men of reproductive age. Environ Health Perspect. 2004; 112(17):1734-40. PMC: 1253667. DOI: 10.1289/ehp.7212. View

11.

Trasande L, Spanier A, Sathyanarayana S, Attina T, Blustein J . Urinary phthalates and increased insulin resistance in adolescents. Pediatrics. 2013; 132(3):e646-55. PMC: 4528350. DOI: 10.1542/peds.2012-4022. View

12.

Sioen I, Fierens T, Van Holderbeke M, Geerts L, Bellemans M, DE Maeyer M . Phthalates dietary exposure and food sources for Belgian preschool children and adults. Environ Int. 2012; 48:102-8. DOI: 10.1016/j.envint.2012.07.004. View

13.

Wormuth M, Scheringer M, Vollenweider M, Hungerbuhler K . What are the sources of exposure to eight frequently used phthalic acid esters in Europeans?. Risk Anal. 2006; 26(3):803-24. DOI: 10.1111/j.1539-6924.2006.00770.x. View

14.

Serrano S, Braun J, Trasande L, Dills R, Sathyanarayana S . Phthalates and diet: a review of the food monitoring and epidemiology data. Environ Health. 2014; 13(1):43. PMC: 4050989. DOI: 10.1186/1476-069X-13-43. View

15.

Trasande L, Sathyanarayana S, Spanier A, Trachtman H, Attina T, Urbina E . Urinary phthalates are associated with higher blood pressure in childhood. J Pediatr. 2013; 163(3):747-53.e1. PMC: 4074773. DOI: 10.1016/j.jpeds.2013.03.072. View

16.

Skakkebaek N, Rajpert-De Meyts E, Main K . Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects. Hum Reprod. 2001; 16(5):972-8. DOI: 10.1093/humrep/16.5.972. View

17.

Colacino J, Harris T, Schecter A . Dietary intake is associated with phthalate body burden in a nationally representative sample. Environ Health Perspect. 2010; 118(7):998-1003. PMC: 2920922. DOI: 10.1289/ehp.0901712. View

18.

Bradley E, Burden R, Leon I, Mortimer D, Speck D, Castle L . Determination of phthalate diesters in foods. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2013; 30(4):722-34. DOI: 10.1080/19440049.2013.781683. View

19.

Gonzalez-Castro M, Olea-Serrano M, Rivas-Velasco A, Medina-Rivero E, Ordonez-Acevedo L, De Leon-Rodriguez A . Phthalates and bisphenols migration in Mexican food cans and plastic food containers. Bull Environ Contam Toxicol. 2011; 86(6):627-31. DOI: 10.1007/s00128-011-0266-3. View

20.

Schecter A, Lorber M, Guo Y, Wu Q, Yun S, Kannan K . Phthalate concentrations and dietary exposure from food purchased in New York State. Environ Health Perspect. 2013; 121(4):473-94. PMC: 3620091. DOI: 10.1289/ehp.1206367. View