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Limb Saving Procedure in Metastatic Leiomyosarcoma of the Femoral Vein: Case Report and Literature Review

Overview
Journal Indian J Surg
Specialty General Surgery
Date 2015 May 15
PMID 25972629
Citations 1
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Abstract

Primary venous leiomyosarcoma is very rare and first description was made by Perl in 1871. Most cases are from venous system and half of them are reported to originate in inferior vena cava. We report the case of a 77-year-old Caucasian man with a leiomyosarcoma of the femoral vein. A leg preservation surgery was decided. Eight months later, the patient died of tumor progression. A PubMed search using the terms "leiomyosarcoma femoral vein" and "leiomyosarcoma vein" was performed. All cases of composite iliac-femoral leiomyosarcoma were excluded, and as far as possible, only well-documented cases were included. Median age was 55 years, seven men and six women, tumor resection was performed by six authors, six others performed a vascular resection, and one preferred for a thigh excision. Prognosis remains poor if metastasis is present, and in these cases, a conservative surgery is recommended to preserve patients' quality of life.

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Leiomyosarcoma presenting as 'idiopathic' unilateral lower limb lymphoedema.

Abd Kadir H, Naik J, Chandrasekar C BMJ Case Rep. 2017; 2017.

PMID: 29066633 PMC: 5665209. DOI: 10.1136/bcr-2017-219898.

References
1.
Hines O, Nelson S, Quinones-Baldrich W, Eilber F . Leiomyosarcoma of the inferior vena cava: prognosis and comparison with leiomyosarcoma of other anatomic sites. Cancer. 1999; 85(5):1077-83. View

2.
Iwata J, Fletcher C . Immunohistochemical detection of cytokeratin and epithelial membrane antigen in leiomyosarcoma: a systematic study of 100 cases. Pathol Int. 2000; 50(1):7-14. DOI: 10.1046/j.1440-1827.2000.01001.x. View

3.
Pervaiz N, Colterjohn N, Farrokhyar F, Tozer R, Figueredo A, Ghert M . A systematic meta-analysis of randomized controlled trials of adjuvant chemotherapy for localized resectable soft-tissue sarcoma. Cancer. 2008; 113(3):573-81. DOI: 10.1002/cncr.23592. View

4.
Dinis da Gama A, Cabral G, Ministro A, Evangelista A, Damiao A, Fernandes A . [Leiomyosarcoma of the superficial femoral vein. Case report]. Rev Port Cir Cardiotorac Vasc. 2009; 16(2):97-101. View

5.
de Saint Aubain Somerhausen N, Fletcher C . Leiomyosarcoma of soft tissue in children: clinicopathologic analysis of 20 cases. Am J Surg Pathol. 1999; 23(7):755-63. DOI: 10.1097/00000478-199907000-00002. View