Defining the Molecular Landscape of Ependymomas

Overview

Journal Cancer Cell

Publisher Cell Press

Specialty Oncology

Date 2015 May 13

PMID 25965568

Citations 10

Authors

Tenley C Archer

Scott L Pomeroy

Affiliations

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Abstract

Ependymomas have a variable prognosis. In this issue of Cancer Cell, Pajtler and colleagues identify nine subgroups of ependymoma using DNA methylation profiles. Two subgroups, predominately pediatric, are responsible for most of the mortality, with all others having nearly 100% overall survival after 5 years.

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Citation analysis of the most influential ependymoma research articles illustrates improved knowledge of the molecular biology of ependymoma.

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Supratentorial pediatric cortical ependymomas: a comprehensive retrospective study.

Wang Q, Cheng J, Zhang S, Li Q, Hui X, Ju Y Neurosurg Rev. 2020; 44(3):1543-1551.

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