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Effectiveness of a Nurse-managed Protocol to Prevent Hypoglycemia in Hospitalized Patients with Diabetes

Overview
Journal J Diabetes Res
Publisher Wiley
Specialty Endocrinology
Date 2015 May 12
PMID 25961051
Citations 1
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Abstract

Background: Hypoglycemia due to inadequate carbohydrate intake is a frequent complication of insulin treatment of diabetic in-patients. Objective. To assess the effectiveness of a nurse-managed protocol to prevent hypoglycemia during subcutaneous insulin treatment.

Design: Prospective pre-post-intervention study.

Methods: In 350 consecutive diabetic in-patients the incidence of hypoglycemia (blood glucose < 70 mg/dL) during subcutaneous insulin treatment was assessed before (phase A) and after (phase B) the protocol was adopted to permit (1) the patient to opt for substitutive food to integrate incomplete carbohydrate intake in the meal; (2) in case of lack of appetite or repeatedly partial intake of the planned food, prandial insulin administered at the end of the meal to be related to the actual amount of carbohydrates eaten; (3) intravenous infusion of glucose during prolonged fasting.

Results: Eighty-four patients in phase A and 266 in phase B received subcutaneous insulin for median periods of, respectively, 7 (Q1-Q3 6-12) and 6 days (Q1-Q3 4-9). Hypoglycemic events declined significantly from 0.34 ± 0.33 per day in phase A to 0.19 ± 0.30 in phase B (P > 0.001).

Conclusions: A nurse-managed protocol focusing on carbohydrate intake reduced the incidence of hypoglycemia in patients with diabetes receiving subcutaneous insulin in hospital.

Citing Articles

Development and Validation of a Hypoglycemia Risk Model for Intensive Insulin Therapy in Patients with Type 2 Diabetes.

Hu X, Xu W, Lin S, Zhang C, Ling C, Chen M J Diabetes Res. 2020; 2020:7292108.

PMID: 33015194 PMC: 7525304. DOI: 10.1155/2020/7292108.

References
1.
Umpierrez G, Smiley D, Zisman A, Prieto L, Palacio A, Ceron M . Randomized study of basal-bolus insulin therapy in the inpatient management of patients with type 2 diabetes (RABBIT 2 trial). Diabetes Care. 2007; 30(9):2181-6. DOI: 10.2337/dc07-0295. View

2.
Dendy J, Chockalingam V, Tirumalasetty N, Dornelles A, Blonde L, Bolton P . Identifying risk factors for severe hypoglycemia in hospitalized patients with diabetes. Endocr Pract. 2014; 20(10):1051-6. DOI: 10.4158/EP13467.OR. View

3.
Moghissi E, Korytkowski M, DiNardo M, Einhorn D, Hellman R, Hirsch I . American Association of Clinical Endocrinologists and American Diabetes Association consensus statement on inpatient glycemic control. Diabetes Care. 2009; 32(6):1119-31. PMC: 2681039. DOI: 10.2337/dc09-9029. View

4.
Avanzini F, Marelli G, Donzelli W, Sorbara L, Palazzo E, Bellato L . Hyperglycemia during acute coronary syndrome: a nurse-managed insulin infusion protocol for stricter and safer control. Eur J Cardiovasc Nurs. 2009; 8(3):182-9. DOI: 10.1016/j.ejcnurse.2008.12.001. View

5.
Goyal A, Mehta S, Diaz R, Gerstein H, Afzal R, Xavier D . Differential clinical outcomes associated with hypoglycemia and hyperglycemia in acute myocardial infarction. Circulation. 2009; 120(24):2429-37. DOI: 10.1161/CIRCULATIONAHA.108.837765. View