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Neuroinvasive Cryptococcosis in an Immunocompetent Patient with a Negative Spinal Fluid Cryptococcus Antigen

Overview
Journal Case Rep Infect Dis
Publisher Wiley
Specialty Infectious Diseases
Date 2015 May 9
PMID 25954558
Citations 2
Authors
Rocio C Garcia-Santibanez
Veenu Gill
Stanley Yancovitz
Dewitt Pyburn
Affiliations
Soon will be listed here.
Abstract

58-year-old man presented with headache, nausea, vomiting, and gait disturbance. Brain MRI showed meningeal enhancement and herniation. Serum Cryptococcus antigen was positive but spinal fluid antigen and cultures were negative. A cerebellar biopsy revealed nonencapsulated Cryptococcus. He completed antifungal therapy. Serum Cryptococcus antigen titer decreased. He had a full neurological recovery.

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