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Multiresistant Bacterial Infections in Liver Cirrhosis: Clinical Impact and New Empirical Antibiotic Treatment Policies

Overview
Journal World J Hepatol
Specialty Gastroenterology
Date 2015 May 9
PMID 25954474
Citations 14
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Abstract

Recently, important changes have been reported regarding the epidemiology of bacterial infections in liver cirrhosis. There is an emergence of multiresistant bacteria in many European countries and also worldwide, including the United States and South Korea. The classic empirical antibiotic treatment (third-generation cephalosporins, e.g., ceftriaxone, cefotaxime or amoxicillin-clavulanic acid) is still effective in infections acquired in the community, but its failure rate in hospital acquired infections and in some health-care associated infections is high enough to ban its use in these settings. The current editorial focuses on the different epidemiology of bacterial infections in cirrhosis across countries and on its therapeutic implications.

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