Improving Recognition of Hepatic Perivascular Epithelioid Cell Tumor: Case Report and Literature Review

Overview

Journal World J Gastroenterol

Publisher Baishideng Publishing Group

Specialty Gastroenterology

Date 2015 May 9

PMID 25954119

Citations 25

Authors

Toshiya Maebayashi

Katsumi Abe

Takuya Aizawa

Masakuni Sakaguchi

Naoya Ishibashi

Osamu Abe

Tadatoshi Takayama

Hisashi Nakayama

Shunichi Matsuoka

Kazushige Nirei

Hitomi Nakamura

Masahiro Ogawa

Masahiko Sugitani

Affiliations

Soon will be listed here.

Abstract

A 58-year-old man presented with the chief complaint of abdominal bloating and was incidentally found to have a liver tumor. As diagnostic imaging studies could not rule out malignancy, the patient underwent partial resection of segment 3 of the liver. The lesion pathologically showed eosinophilic proliferation, in addition to immunohistochemical positivity for human melanoma black 45 and Melan-A, thereby leading to the diagnosis of a hepatic perivascular epithelioid cell tumor (PEComa). A PEComa arising from the liver is relatively rare. Moreover, the name 'PEComa' has not yet been widely recognized, and the same disease entity has been called epithelioid angiomyolipoma (EAML), further diminishing the recognition of PEComa. In addition, PEComa imaging findings mimic those of malignant liver tumors, and clinically, this tumor tends to enlarge. Therefore, a PEComa is difficult to diagnose. We conducted a systematic review of PEComa and EAML cases and discuss the results, including findings useful for differentiating perivascular epithelioid cell tumors from malignant liver tumors.

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