Confounding Effect of Cyclosporine Dosing when Comparing Horse and Rabbit Antithymocyte Globulin in Patients with Severe Aplastic Anemia

Overview

Journal Haematologica

Specialty Hematology

Date 2015 May 7

PMID 25944638

Citations 2

Authors

Nathalie Bleyzac

Michael Philippe

Amandine Bertrand

Yves Bertrand

Affiliations

Soon will be listed here.

Citing Articles

Clinical Outcome of Acquired Post-Immunosuppressive-Therapy Aplastic Anemia in Pediatric Patients: A 13-Year Experience in Two Southern China Tertiary Care Centers.

Huang J, Huang L, Liu S, Lin S, Cheng Y, Jiang X Int J Gen Med. 2021; 14:3133-3144.

PMID: 34239322 PMC: 8259937. DOI: 10.2147/IJGM.S313898.

Answer to "Confounding effect of cyclosporine dosing when comparing horse and rabbit antithymocyte globulin in patients with severe aplastic anemia".

Feng X, Scheinberg P, Young N Haematologica. 2015; 100(5):e213.

PMID: 25944639 PMC: 4420236. DOI: 10.3324/haematol.2015.124446.

References

Bacigalupo A, Bruno B, Saracco P, Di Bona E, Locasciulli A, Locatelli F . Antilymphocyte globulin, cyclosporine, prednisolone, and granulocyte colony-stimulating factor for severe aplastic anemia: an update of the GITMO/EBMT study on 100 patients. European Group for Blood and Marrow Transplantation (EBMT) Working Party on.... Blood. 2000; 95(6):1931-4. View

Feng X, Scheinberg P, Biancotto A, Rios O, Donaldson S, Wu C . In vivo effects of horse and rabbit antithymocyte globulin in patients with severe aplastic anemia. Haematologica. 2014; 99(9):1433-40. PMC: 4562531. DOI: 10.3324/haematol.2014.106542. View

Stein C, Murray J, Wood A . Inhibition of stimulated interleukin-2 production in whole blood: a practical measure of cyclosporine effect. Clin Chem. 1999; 45(9):1477-84. View

Kawai M, Kitade H, Mathieu C, Waer M, Pirenne J . Inhibitory and stimulatory effects of cyclosporine A on the development of regulatory T cells in vivo. Transplantation. 2005; 79(9):1073-7. DOI: 10.1097/01.tp.0000153505.73700.32. View

Feng X, Kajigaya S, Solomou E, Keyvanfar K, Xu X, Raghavachari N . Rabbit ATG but not horse ATG promotes expansion of functional CD4+CD25highFOXP3+ regulatory T cells in vitro. Blood. 2008; 111(7):3675-83. PMC: 2275026. DOI: 10.1182/blood-2008-01-130146. View

Sewgobind V, van der Laan L, Klepper M, IJzermans J, Tilanus H, Weimar W . Functional analysis of CD4+ CD25bright T cells in kidney transplant patients: improving suppression of donor-directed responses after transplantation. Clin Transplant. 2008; 22(5):579-86. DOI: 10.1111/j.1399-0012.2008.00827.x. View

Brandt C, Pavlovic V, Radbruch A, Worm M, Baumgrass R . Low-dose cyclosporine A therapy increases the regulatory T cell population in patients with atopic dermatitis. Allergy. 2009; 64(11):1588-96. DOI: 10.1111/j.1398-9995.2009.02054.x. View

Sewgobind V, van der Laan L, Kho M, Kraaijeveld R, Korevaar S, van Dam T . Characterization of rabbit antithymocyte globulins-induced CD25+ regulatory T cells from cells of patients with end-stage renal disease. Transplantation. 2010; 89(6):655-66. DOI: 10.1097/TP.0b013e3181c9cc7a. View

Atta E, Dias D, Marra V, de Azevedo A . Comparison between horse and rabbit antithymocyte globulin as first-line treatment for patients with severe aplastic anemia: a single-center retrospective study. Ann Hematol. 2010; 89(9):851-9. DOI: 10.1007/s00277-010-0944-y. View

10.

Gerard C, Bleyzac N, Girard P, Freyer G, Bertrand Y, Tod M . Influence of dosing schedule on organ exposure to cyclosporin in pediatric hematopoietic stem cell transplantation: analysis with a PBPK model. Pharm Res. 2010; 27(12):2602-13. DOI: 10.1007/s11095-010-0252-1. View

11.

Scheinberg P, Nunez O, Weinstein B, Scheinberg P, Biancotto A, Wu C . Horse versus rabbit antithymocyte globulin in acquired aplastic anemia. N Engl J Med. 2011; 365(5):430-8. PMC: 3721503. DOI: 10.1056/NEJMoa1103975. View

12.

Shi J, Ge M, Lu S, Li X, Shao Y, Huang J . Intrinsic impairment of CD4(+)CD25(+) regulatory T cells in acquired aplastic anemia. Blood. 2012; 120(8):1624-32. DOI: 10.1182/blood-2011-11-390708. View

13.

Sutton K, Shereck E, Nemecek E, Kurre P . Immune markers of disease severity and treatment response in pediatric acquired aplastic anemia. Pediatr Blood Cancer. 2012; 60(3):455-60. DOI: 10.1002/pbc.24247. View

14.

Bertrand A, Philippe M, Bertrand Y, Plantaz D, Bleyzac N . Salvage therapy of refractory severe aplastic anemia by decreasing cyclosporine dose regimen. Eur J Haematol. 2013; 92(2):172-6. DOI: 10.1111/ejh.12220. View

15.

Kennedy-Nasser A, Ku S, Castillo-Caro P, Hazrat Y, Wu M, Liu H . Ultra low-dose IL-2 for GVHD prophylaxis after allogeneic hematopoietic stem cell transplantation mediates expansion of regulatory T cells without diminishing antiviral and antileukemic activity. Clin Cancer Res. 2014; 20(8):2215-25. PMC: 3989436. DOI: 10.1158/1078-0432.CCR-13-3205. View