[Evaluation of the Results of the Treatment of Infections in Newborn Infants with Developmental Anomalies of the Facial Bones]

A clinical course and the results of treatment of infections in 53 neonates with visceral cranium defects are discussed. The analysis included the type of defect, immunity and the causes of therapeutical failures. Developmental defects of other organs coexisted with visceral Cranium defects in 45% of the neonates. High incidence of aspiration pneumonia (in 57%) with unfavourable prognosis (40%) was observed despite an intensive respiratory therapy including assisted ventilation. Therapeutical failures were caused by the coexistence of other developmental anomalies (found in 80% od deceased neonates) and low body weight at birth (35% of deaths). No immunological disorders were found except sporadic deficit of immunoglobulins and T-cells. Prophylaxis is of utmost importance. It includes: early orthodontic correction and introduction of the appropriate feeding technique at the neonatal wards.