Recent Advances and Applications of Experimental Technologies in Marine Natural Product Research

Overview

Journal Mar Drugs

Publisher MDPI

Specialties Biology
Pharmacology

Date 2015 May 5

PMID 25939037

Citations 11

Authors

Ke Li

Yu-Wen Chung-Davidson

Ugo Bussy

Weiming Li

Affiliations

Soon will be listed here.

Abstract

Marine natural products are a rich source of novel and biologically active compounds. The number of identified marine natural compounds has grown 20% over the last five years from 2009 to 2013. Several challenges, including sample collection and structure elucidation, have limited the development of this research field. Nonetheless, new approaches, such as sampling strategies for organisms from extreme ocean environments, nanoscale NMR and computational chemistry for structural determination, are now available to overcome the barriers. In this review, we highlight the experimental technology innovations in the field of marine natural products, which in our view will lead to the development of many new drugs in the future.

Citing Articles

Plant and marine-derived natural products: sustainable pathways for future drug discovery and therapeutic development.

Ahmad M, Tahir M, Hong Z, Zia M, Rafeeq H, Ahmad M Front Pharmacol. 2025; 15():1497668.

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UHPLC-QQQ-MS and RP-HPLC Detection of Bioactive Alizarin and Scopoletin Metabolites from Root Extracts and Their Antitubercular, Antibacterial, and Antioxidant Activities.

Sam-Ang P, Phanumartwiwath A, Liana D, Sureram S, Hongmanee P, Kittakoop P ACS Omega. 2023; 8(32):29615-29624.

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Seaweeds in the Oncology Arena: Anti-Cancer Potential of Fucoidan as a Drug-A Review.

Jin J, Yadav D, Madhwani K, Puranik N, Chavda V, Song M Molecules. 2022; 27(18).

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Marine Cyanobacteria as Sources of Lead Anticancer Compounds: A Review of Families of Metabolites with Cytotoxic, Antiproliferative, and Antineoplastic Effects.

Robles-Banuelos B, Duran-Riveroll L, Rangel-Lopez E, Perez-Lopez H, Gonzalez-Maya L Molecules. 2022; 27(15).

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Approaches to Configuration Determinations of Flexible Marine Natural Products: Advances and Prospects.

Huo Z, Zhu F, Zhang X, Zhang X, Liang H, Yao J Mar Drugs. 2022; 20(5).

PMID: 35621984 PMC: 9143581. DOI: 10.3390/md20050333.

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