Analysis of the Factors That Have an Effect on Hypocalcemia Following Thyroidectomy

Overview

Journal Ulus Cerrahi Derg

Specialty General Surgery

Date 2015 May 2

PMID 25931872

Citations 12

Authors

Doga Kalyoncu

Dogan Gonullu

Mehmet Lari Gedik

Muzaffer Er

Erol Kuroglu

Aysenur A Igdem

Ferda Nihat Koksoy

Affiliations

Soon will be listed here.

Abstract

Objective: The incidence of and risk factors for hypocalcemia following thyroidectomy were evaluated in this study.

Material And Methods: One hundred and ninety thyroidectomy patients were evaluated retrospectively for factors that might contribute to postoperative hypocalcemia; age, hyperthyroidism, malignancy, the extent of surgery (total/near total/subtotal thyroidectomy), cervical lymph node dissection, and incidental parathyroidectomy.

Results: The rate of transient hypocalcemia/hypoparathyroidism was 19.47%, with a permanent hypoparathyroidism rate of 4.74%. Factors affecting the development of transient hypocalcemia were found as being operated for hyperthyroidism, and use of total thyroidectomy as the surgical method. Total thyroidectomy increased the risk of postoperative hypocalcemia by 3.16 fold. Patients undergoing operations for hyperthyroidism had a 2.3 fold increase, and those undergoing total thyroidectomy had a 3.16 fold risk of postoperative hypocalcemia.

Conclusion: Hyperthyroidism surgery and total thyroidectomy lead to a higher risk of developing early postoperative or transient hypocalcemia. According to our results, no significant relationship could be established between any of the study parameters and persistent hypocalcemia.

Citing Articles

Predictors of Postoperative Hypocalcemia and Hypoparathyroidism Following Thyroidectomy in Hanoi, Vietnam.

Do K, Duong P, Phung T, Duong Y, Hoang G, Le H Int J Endocrinol Metab. 2025; 22(2):e146358.

PMID: 40071247 PMC: 11892512. DOI: 10.5812/ijem-146358.

Incidental Parathyroidectomy After Thyroid Surgery: A Single-Center Study.

Granata R, Zanghi A, Scribano M, Riccioli G, Privitera F, La Vignera S Biomedicines. 2024; 12(10).

PMID: 39457684 PMC: 11505326. DOI: 10.3390/biomedicines12102372.

A Comparison of Harmonic Scalpel and Conventional Techniques for Thyroidectomy.

Arora R, Prajwal S, Rao K, Singh A, Nagarkar N, Abishek A Indian J Otolaryngol Head Neck Surg. 2023; 75(4):3410-3414.

PMID: 37974807 PMC: 10645797. DOI: 10.1007/s12070-023-04002-x.

The effect of different therapeutic treatments on the frequency of postoperative hypocalcemia in patients with thyroidectomy.

Piyade H, Basoglu M, Gursoy E Turk J Surg. 2023; 39(1):70-75.

PMID: 37275930 PMC: 10234705. DOI: 10.47717/turkjsurg.2023.5886.

Comparison of Transoral Endoscopic Thyroidectomy Vestibular Approach and Conventional Open Thyroidectomy in Benign Thyroid Tumors.

Xuan Nguyen H, Nguyen H, Le A, Le Q Indian J Surg Oncol. 2022; 13(1):178-183.

PMID: 35462668 PMC: 8986896. DOI: 10.1007/s13193-022-01494-x.

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