Evaluation of Nasopharyngeal Microbial Flora and Antibiogram and Its Relation to Otitis Media with Effusion

Overview

Journal Eur Arch Otorhinolaryngol

Specialty Otorhinolaryngology

Date 2015 May 2

PMID 25929414

Citations 2

Authors

Navid Nourizadeh

Kiarash Ghazvini

Vahideh Gharavi

Niloufar Nourizadeh

Rahman Movahed

Affiliations

Soon will be listed here.

Abstract

Acute otitis media and otitis media with effusion (OME) are the main causes of hearing impairment in children which require proper treatment, mainly antibiotic therapy. Patients whom were appropriate candidates for adenoidectomy were divided into two groups regarding the presence of middle ear effusion. Adenoid tissue specimens were cultured in both groups and the bacterial flora and anti-microbial resistance pattern were determined. 72 patients were studied, 42 % had OME while 58 % did not. The following bacteria were isolated and cultured from both groups with no meaningful difference in prevalence: Streptococcus viridans (p = 0.265), Staphylococcus aureus (p = 0.72), H. influenza (p = 0.806), Entrococcus. spp (0.391), Streptococcus pneumonia (p = 0.391), nonhemolytic Streptococcus (p = 0.230). Bacterial sensitivity was similar for Amoxicillin-clavulanate (p = 0.935), Amoxicillin (p = 0.935), Cephalexin (p = 0.806), Cefixime (p = 0.391) and Azithromycin in both groups. The two groups showed no meaningful difference considering the bacterial flora of nasopharynx and their sensitivity. Bacteria in both groups were sensitive to Amoxicillin and Amoxicillin-clavulanate and resistant to Azithromycin, Cefixime and Cephalexin.

Citing Articles

Risk factors for persistent otitis media with effusion in children: a case-control study.

Lee J, Kim S, Song C, Kim Y, Kim Y, Choi J Yeungnam Univ J Med. 2019; 35(1):70-75.

PMID: 31620573 PMC: 6784671. DOI: 10.12701/yujm.2018.35.1.70.

Resistant Streptococcus pneumoniae strains in children with acute otitis media- high risk of persistent colonization after treatment.

Korona-Glowniak I, Zychowski P, Siwiec R, Mazur E, Niedzielska G, Malm A BMC Infect Dis. 2018; 18(1):478.

PMID: 30253754 PMC: 6156860. DOI: 10.1186/s12879-018-3398-9.

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