» Articles » PMID: 25928876

Expert Opinion on the Management of Pain in Hospitalised Older Patients with Cognitive Impairment: a Mixed Methods Analysis of a National Survey

Overview
Journal BMC Geriatr
Publisher Biomed Central
Specialty Geriatrics
Date 2015 May 1
PMID 25928876
Citations 5
Authors
Affiliations
Soon will be listed here.
Abstract

Background: Hospitalised older patients are complex. Comorbidity and polypharmacy complicate frailty. Significant numbers have dementia and/or cognitive impairment. Pain is highly prevalent. The evidence base for pain management in cognitively impaired individuals is sparse due to methodological issues. A wealth of expert opinion is recognised potentially providing a useful evidence base for guiding clinical practice. The study aimed to gather expert opinion on pain management in cognitively impaired hospitalised older people.

Methods: Consultant Geriatricians listed as dementia leads in the National Dementia Audit were contacted electronically and invited to respond. The questionnaire sought information on their role, confidence and approach to pain management in cognitively impaired hospitalised patients. Responses were analysed using a mixed methods approach.

Results: Respondents considered themselves very confident in the clinical field. Awareness of potential to do harm was highly evident. Unequivocally responses suggested paracetamol is safe and should be first choice analgesic, newer opiates should be used preferentially in renal impairment and nefopam is unsafe. A grading of the safety profile of specific medications became apparent, prompting requirement for further evaluation and holistic assessment.

Conclusion: The lack of consensus reached highlights the complexity of this clinical field. The use of paracetamol first line, newer opiates in renal impairment and avoidance of nefopam are immediately transferrable to clinical practice. Further review, evaluation and comparison of the risks associated with other specific analgesics are necessary before a comprehensive clinical guideline can be produced.

Citing Articles

Informal caregivers' burden and chronic pain in older adults: a dyadic study unveiling the correlation and its impact.

Tse M, Ng S, Lou V, Lo R, Cheung D, Lee P Pain Manag. 2025; 15(3):123-130.

PMID: 39968813 PMC: 11881828. DOI: 10.1080/17581869.2025.2467614.


Pharmacological Pain Treatment in Older Persons.

Pickering G, Kotlinska-Lemieszek A, Krcevski Skvarc N, OMahony D, Monacelli F, Knaggs R Drugs Aging. 2024; 41(12):959-976.

PMID: 39465454 PMC: 11634925. DOI: 10.1007/s40266-024-01151-8.


The Difficulties of Managing Pain in People Living with Frailty: The Potential for Digital Phenotyping.

Collins J, Walsh D, Gladman J, Patrascu M, Husebo B, Adam E Drugs Aging. 2024; 41(3):199-208.

PMID: 38401025 PMC: 10925563. DOI: 10.1007/s40266-024-01101-4.


Pain management for people with dementia: a cross-setting systematic review and meta-ethnography.

Smith T, Lockey D, Johnson H, Rice L, Heard J, Irving L Br J Pain. 2023; 17(1):6-22.

PMID: 36815066 PMC: 9940246. DOI: 10.1177/20494637221119588.


Paracetamol (acetaminophen) rescues cognitive decline, neuroinflammation and cytoskeletal alterations in a model of post-operative cognitive decline (POCD) in middle-aged rats.

Garrone B, Durando L, Prenderville J, Sokolowska E, Milanese C, Di Giorgio F Sci Rep. 2021; 11(1):10139.

PMID: 33980934 PMC: 8115335. DOI: 10.1038/s41598-021-89629-y.


References
1.
Morrison R, Siu A . A comparison of pain and its treatment in advanced dementia and cognitively intact patients with hip fracture. J Pain Symptom Manage. 2000; 19(4):240-8. DOI: 10.1016/s0885-3924(00)00113-5. View

2.
Frampton M . Experience assessment and management of pain in people with dementia. Age Ageing. 2003; 32(3):248-51. DOI: 10.1093/ageing/32.3.248. View

3.
McAuliffe L, Nay R, ODonnell M, Fetherstonhaugh D . Pain assessment in older people with dementia: literature review. J Adv Nurs. 2008; 65(1):2-10. DOI: 10.1111/j.1365-2648.2008.04861.x. View

4.
Horgas A, Tsai P . Analgesic drug prescription and use in cognitively impaired nursing home residents. Nurs Res. 1998; 47(4):235-42. DOI: 10.1097/00006199-199807000-00009. View

5.
Dawson P . Cognitively impaired residents receive less pain medication than non-cognitively impaired residents. Perspectives. 1999; 22(4):16-7. View