Soft Tissue Sarcomas of the Kidney

Overview

Journal Rare Tumors

Publisher Sage Publications

Specialty Oncology

Date 2015 Apr 29

PMID 25918607

Citations 2

Authors

Olivia Kohle

Dominik Abt

Christian Rothermundt

Christian Ohlschlegel

Christiane Brugnolaro

Hans-Peter Schmid

Affiliations

Soon will be listed here.

Abstract

Soft tissue sarcomas are rare mesenchymal tumors. Amongst others, primitive neuroectodermal tumors (PNET) of the kidney and synovial sarcoma of the kidney belong to the group of soft tissue sarcomas. Synovial sarcomas can occur almost anywhere in the body, most frequently, however, in the lower (62%) or upper extremities (21%). Metastases occur in 50-70% of cases, and thus the prognosis is poor. PNETs are rare, highly aggressive neoplastic lesions which mainly occur in the torso or axial skeleton in young adults. The prognosis is poor with a 5-year disease-free survival rate of 45-55%. The primary therapeutic approach is surgical resection. Most randomized studies assessing adjuvant chemotherapy for all types of localized soft tissue sarcomas did not show statistically significantly better overall survival times after chemotherapy, although they did show longer progression-free survival. We report on two cases of primary renal synovial sarcoma and one case of PNET of the kidney.

Citing Articles

Primary Renal Synovial Sarcoma: A Rare Case Presentation.

Abbas M, Majeed M, Liaqat M, Bano S, Khalid T, Chaudhry N Cureus. 2024; 16(10):e72256.

PMID: 39583501 PMC: 11584758. DOI: 10.7759/cureus.72256.

Primary synovial sarcoma of the kidney: a case report of complete pathological response at a Lebanese tertiary care center.

El Chediak A, Mukherji D, Temraz S, Nassif S, Sinno S, Mahfouz R BMC Urol. 2018; 18(1):40.

PMID: 29751751 PMC: 5948733. DOI: 10.1186/s12894-018-0358-z.

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