Distribution of Glial Fibrillary Acidic Protein (GFAP)-immunoreactive Astrocytes in the Rat Brain. II. Mesencephalon, Rhombencephalon and Spinal Cord

Overview

Journal Exp Brain Res

Specialty Neurology

Date 1989 Jan 1

PMID 2591510

Citations 19

Authors

F Hajos

M Kalman

Affiliations

Soon will be listed here.

Abstract

The topographical mapping of glial fibrillary acidic protein (GFAP)-immunoreactivity was performed in coronal serial sections of the rat mesencephalon, rhombencephalon and spinal cord. Relative to a background of poor or moderate overall staining of the mesencephalon, the interpeduncular nucleus, substantia nigra and the periaqueductal grey matter were prominent by their intense GFAP-immunoreactivity. The pons and particularly the medulla contained more GFAP-labelled elements compared with the mesencephalon. The spinal trigeminal nucleus and Rolando substance were distinguished by their intense staining. Large fibre tracts were usually poor in immunoreactive GFAP. In a concluding discussion, findings relevant to the GFAP-mapping of the whole rat CNS are evaluated with regard to possible reasons underlying the observed differential distribution of GFAP-immunoreactivity.

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