Eighty Years of Research on Islet Amyloidosis in Uppsala

Overview

Journal Ups J Med Sci

Specialty General Medicine

Date 2015 Apr 24

PMID 25903284

Authors

Gunilla T Westermark

Marie Oskarsson

Arne Andersson

Per Westermark

Affiliations

Soon will be listed here.

References

Westermark P, Grimelius L . The pancreatic islet cells in insular amyloidosis in human diabetic and non-diabetic adults. Acta Pathol Microbiol Scand A. 1973; 81(3):291-300. DOI: 10.1111/j.1699-0463.1973.tb03538.x. View

Glenner G, Eanes E, Bladen H, Linke R, Termine J . Beta-pleated sheet fibrils. A comparison of native amyloid with synthetic protein fibrils. J Histochem Cytochem. 1974; 22(12):1141-58. DOI: 10.1177/22.12.1141. View

Lundgren G, Andersson A, Borg H, Buschard K, Groth C, Gunnarsson R . Structural and functional integrity of isolated human islets of langerhans maintained in tissue culture for 1-3 weeks. Transplant Proc. 1977; 9(1):237-40. View

Glenner G, Wong C . Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem Biophys Res Commun. 1984; 120(3):885-90. DOI: 10.1016/s0006-291x(84)80190-4. View

Oskarsson M, Paulsson J, Schultz S, Ingelsson M, Westermark P, Westermark G . In vivo seeding and cross-seeding of localized amyloidosis: a molecular link between type 2 diabetes and Alzheimer disease. Am J Pathol. 2015; 185(3):834-46. DOI: 10.1016/j.ajpath.2014.11.016. View

Sipe J, Benson M, Buxbaum J, Ikeda S, Merlini G, Saraiva M . Nomenclature 2014: Amyloid fibril proteins and clinical classification of the amyloidosis. Amyloid. 2014; 21(4):221-4. DOI: 10.3109/13506129.2014.964858. View

Eisenberg D, Jucker M . The amyloid state of proteins in human diseases. Cell. 2012; 148(6):1188-203. PMC: 3353745. DOI: 10.1016/j.cell.2012.02.022. View

Law E, Lu S, Kieffer T, Warnock G, Ao Z, Woo M . Differences between amyloid toxicity in alpha and beta cells in human and mouse islets and the role of caspase-3. Diabetologia. 2010; 53(7):1415-27. DOI: 10.1007/s00125-010-1717-9. View

Jurgens C, Toukatly M, Fligner C, Udayasankar J, Subramanian S, Zraika S . β-cell loss and β-cell apoptosis in human type 2 diabetes are related to islet amyloid deposition. Am J Pathol. 2011; 178(6):2632-40. PMC: 3123989. DOI: 10.1016/j.ajpath.2011.02.036. View

10.

Potter K, Abedini A, Marek P, Klimek A, Butterworth S, Driscoll M . Islet amyloid deposition limits the viability of human islet grafts but not porcine islet grafts. Proc Natl Acad Sci U S A. 2010; 107(9):4305-10. PMC: 2840144. DOI: 10.1073/pnas.0909024107. View

11.

Westermark G, Westermark P, Berne C, Korsgren O . Widespread amyloid deposition in transplanted human pancreatic islets. N Engl J Med. 2008; 359(9):977-9. DOI: 10.1056/NEJMc0802893. View

12.

Ryan E, Paty B, Senior P, Bigam D, Alfadhli E, Kneteman N . Five-year follow-up after clinical islet transplantation. Diabetes. 2005; 54(7):2060-9. DOI: 10.2337/diabetes.54.7.2060. View

13.

Westermark P, Andersson A, Westermark G . Is aggregated IAPP a cause of beta-cell failure in transplanted human pancreatic islets?. Curr Diab Rep. 2005; 5(3):184-8. DOI: 10.1007/s11892-005-0007-2. View

14.

EHRLICH J, RATNER I . Amyloidosis of the islets of Langerhans. A restudy of islet hyalin in diabetic and non-diabetic individuals. Am J Pathol. 1961; 38:49-59. PMC: 1942321. View

15.

Cohen A, CALKINS E . Electron microscopic observations on a fibrous component in amyloid of diverse origins. Nature. 1959; 183(4669):1202-3. DOI: 10.1038/1831202a0. View

16.

Westermark G, Westermark P, Eizirik D, HELLERSTROM C, Fox N, Steiner D . Differences in amyloid deposition in islets of transgenic mice expressing human islet amyloid polypeptide versus human islets implanted into nude mice. Metabolism. 1999; 48(4):448-54. DOI: 10.1016/s0026-0495(99)90102-6. View

17.

Westermark P, Eizirik D, Pipeleers D, HELLERSTROM C, Andersson A . Rapid deposition of amyloid in human islets transplanted into nude mice. Diabetologia. 1995; 38(5):543-9. DOI: 10.1007/BF00400722. View

18.

Jansson L, Eizirik D, Pipeleers D, Borg L, HELLERSTROM C, Andersson A . Impairment of glucose-induced insulin secretion in human pancreatic islets transplanted to diabetic nude mice. J Clin Invest. 1995; 96(2):721-6. PMC: 185255. DOI: 10.1172/JCI118115. View

19.

Eizirik D, Pipeleers D, Ling Z, Welsh N, HELLERSTROM C, Andersson A . Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury. Proc Natl Acad Sci U S A. 1994; 91(20):9253-6. PMC: 44790. DOI: 10.1073/pnas.91.20.9253. View

20.

Korsgren O, Jansson L, Eizirik D, Andersson A . Functional and morphological differentiation of fetal porcine islet-like cell clusters after transplantation into nude mice. Diabetologia. 1991; 34(6):379-86. DOI: 10.1007/BF00403174. View