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Results of the National Lung Cancer Screening Trial: Where Are We Now?

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Publisher Elsevier
Date 2015 Apr 23
PMID 25901558
Citations 11
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Abstract

The National Lung Screening Trial was a large, multicenter, randomized controlled trial published in 2011. It found that annual screening with low-dose CT (LDCT) in a high-risk population was associated with a 20% reduction in lung cancer-specific mortality compared with conventional chest radiography. Several leading professional organizations have since put forth lung cancer screening guidelines that include the use of LDCT, largely on the basis of this study. Broad adoption of these screening recommendations, however, remains a challenge.

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