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Current Role of Dexmedetomidine in Clinical Anesthesia and Intensive Care

Overview
Specialty Anesthesiology
Date 2015 Apr 18
PMID 25885374
Citations 108
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Abstract

Dexmedetomidine is a new generation highly selective α2-adrenergic receptor (α2-AR) agonist that is associated with sedative and analgesic sparing effects, reduced delirium and agitation, perioperative sympatholysis, cardiovascular stabilizing effects, and preservation of respiratory function. The aim of this review is to present the most recent topics regarding the advantages in using dexmedetomidine in clinical anesthesia and intensive care, while discussing the controversial issues of its harmful effects.

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