Complete Genome Sequences of Two Helicobacter Pylori Strains from a Canadian Arctic Aboriginal Community

Overview

Journal Genome Announc

Publisher American Society for Microbiology

Date 2015 Apr 18

PMID 25883278

Citations 4

Authors

Dangeruta Kersulyte

M Teresita Bertoli

Sravya Tamma

Monika Keelan

Rachel Munday

Janis Geary

Sander Veldhuyzen Van Zanten

Karen J Goodman

Douglas E Berg

Affiliations

Soon will be listed here.

Abstract

We report here the complete genome sequences of two Amerind Helicobacter pylori strains from Aklavik, Northwest Territories, Canada. One strain contains extra iron-cofactored urease genes and ~140 rearrangements in its chromosome relative to other described strains (typically differing from one another by <10 rearrangements), suggesting that it represents a novel lineage of H. pylori.

Citing Articles

Antibiotic dispensation rates among participants in community-driven health research projects in Arctic Canada.

Williams K, Colquhoun A, Munday R, Goodman K BMC Public Health. 2019; 19(1):949.

PMID: 31307422 PMC: 6631451. DOI: 10.1186/s12889-019-7193-3.

Burden of disease from Helicobacter pylori infection in western Canadian Arctic communities.

Fagan-Garcia K, Geary J, Chang H, McAlpine L, Walker E, Colquhoun A BMC Public Health. 2019; 19(1):730.

PMID: 31185961 PMC: 6560895. DOI: 10.1186/s12889-019-7065-x.

Visualization of consensus genome structure without using a reference genome.

Tada I, Tanizawa Y, Arita M BMC Genomics. 2017; 18(Suppl 2):208.

PMID: 28361716 PMC: 5374595. DOI: 10.1186/s12864-017-3499-7.

Whole Genome Sequence and Phylogenetic Analysis Show Strains from Latin America Have Followed a Unique Evolution Pathway.

Munoz-Ramirez Z, Mendez-Tenorio A, Kato I, Bravo M, Rizzato C, Thorell K Front Cell Infect Microbiol. 2017; 7:50.

PMID: 28293542 PMC: 5328995. DOI: 10.3389/fcimb.2017.00050.

References

Herrera P, Mendez M, Velapatino B, Velapatio B, Santivanez L, Santivaez L . DNA-level diversity and relatedness of Helicobacter pylori strains in shantytown families in Peru and transmission in a developing-country setting. J Clin Microbiol. 2008; 46(12):3912-8. PMC: 2593267. DOI: 10.1128/JCM.01453-08. View

Carter E, Tronrud D, Taber S, Karplus P, Hausinger R . Iron-containing urease in a pathogenic bacterium. Proc Natl Acad Sci U S A. 2011; 108(32):13095-9. PMC: 3156221. DOI: 10.1073/pnas.1106915108. View

Kersulyte D, Lee W, Subramaniam D, Anant S, Herrera P, Cabrera L . Helicobacter Pylori's plasticity zones are novel transposable elements. PLoS One. 2009; 4(9):e6859. PMC: 2731543. DOI: 10.1371/journal.pone.0006859. View

Stoof J, Breijer S, Pot R, van der Neut D, Kuipers E, Kusters J . Inverse nickel-responsive regulation of two urease enzymes in the gastric pathogen Helicobacter mustelae. Environ Microbiol. 2008; 10(10):2586-97. DOI: 10.1111/j.1462-2920.2008.01681.x. View

Cheung J, Goodman K, Girgis S, Bailey R, Morse J, Fedorak R . Disease manifestations of Helicobacter pylori infection in Arctic Canada: using epidemiology to address community concerns. BMJ Open. 2014; 4(1):e003689. PMC: 3902307. DOI: 10.1136/bmjopen-2013-003689. View

Cover T, Blaser M . Helicobacter pylori in health and disease. Gastroenterology. 2009; 136(6):1863-73. PMC: 3644425. DOI: 10.1053/j.gastro.2009.01.073. View

Frenck Jr R, Clemens J . Helicobacter in the developing world. Microbes Infect. 2003; 5(8):705-13. DOI: 10.1016/s1286-4579(03)00112-6. View

Duncan S, Bertoli M, Kersulyte D, Valk P, Tamma S, Segal I . Genome Sequences of Three hpAfrica2 Strains of Helicobacter pylori. Genome Announc. 2013; 1(5). PMC: 3784780. DOI: 10.1128/genomeA.00729-13. View

Cheung J, Goodman K, Munday R, Heavner K, Huntington J, Morse J . Helicobacter pylori infection in Canada's arctic: searching for the solutions. Can J Gastroenterol. 2008; 22(11):912-6. PMC: 2661193. DOI: 10.1155/2008/614538. View

10.

Carraher S, Chang H, Munday R, Goodman K . Helicobacter pylori incidence and re-infection in the Aklavik H. pylori Project. Int J Circumpolar Health. 2013; 72. PMC: 3748458. DOI: 10.3402/ijch.v72i0.21594. View

11.

Kersulyte D, Kalia A, Gilman R, Mendez M, Herrera P, Cabrera L . Helicobacter pylori from Peruvian amerindians: traces of human migrations in strains from remote Amazon, and genome sequence of an Amerind strain. PLoS One. 2010; 5(11):e15076. PMC: 2993954. DOI: 10.1371/journal.pone.0015076. View

12.

Goodman K, Jacobson K, van Zanten S . Helicobacter pylori infection in Canadian and related Arctic Aboriginal populations. Can J Gastroenterol. 2008; 22(3):289-95. PMC: 2662204. DOI: 10.1155/2008/258610. View

13.

Suerbaum S, Michetti P . Helicobacter pylori infection. N Engl J Med. 2002; 347(15):1175-86. DOI: 10.1056/NEJMra020542. View

14.

Kersulyte D, Rossi M, Berg D . Sequence divergence and conservation in genomes of Helicobacter cetorum strains from a dolphin and a whale. PLoS One. 2013; 8(12):e83177. PMC: 3866246. DOI: 10.1371/journal.pone.0083177. View