Detection of a 640-bp Deletion in the Aggregatibacter Actinomycetemcomitans Leukotoxin Promoter Region in Isolates from an Adolescent of Ethiopian Origin

Overview

Journal J Oral Microbiol

Specialty Dentistry

Date 2015 Apr 18

PMID 25881573

Citations 14

Authors

Rolf Claesson

Jan Gudmundson

Carola Hoglund Aberg

Dorte Haubek

Anders Johansson

Affiliations

Soon will be listed here.

Abstract

The expression of the leukotoxin of Aggregatibacter actinomycetemcomitans is regulated by the leukotoxin promoter. A 530-bp deletion or an 886-bp insertion sequence (IS) element in this region has earlier been described in highly leukotoxic isolates. Here, we report on highly leukotoxic isolate with a 640-bp deletion, which was detected in an adolescent of Ethiopian origin.

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