Enteroscopic Sclerotherapy in Blue Rubber Bleb Nevus Syndrome

Overview

Journal Pak J Med Sci

Specialty General Medicine

Date 2015 Apr 17

PMID 25878650

Citations 12

Authors

Shoubin Ning

Yafei Zhang

Zhanfei Zu

Xuyan Mao

Gaoping Mao

Affiliations

Soon will be listed here.

Abstract

Blue rubber bleb nevus syndrome (BRBNS) is a rare syndrome characterized by multiple vascular malformations of varying size and appearance that present predominantly on the skin and within the gastrointestinal tract and, less often, in other internal organs. Gastrointestinal lesions of BRBNS can cause acute or chronic bleeding, and the treatment is challenging. In this case, we reported a successful treatment of vascular malformations in all segments of gastrointestinal tract, including the small intestine, by endoscopic sclerotherapy, in a 10-year-old boy with BRBNS.

Citing Articles

Residual Recurrence of a Small Intestinal Capillary Hemangioma with Obscure Gastrointestinal Bleeding Treated by Double-Balloon Endoscopy: A Case Report and Literature Review.

Nomura K, Shibuya T, Yuzawa A, Omori M, Odakura R, Koma M J Clin Med. 2024; 13(12).

PMID: 38929942 PMC: 11204303. DOI: 10.3390/jcm13123415.

Solitary Ileal Hemangioma in a 3-year-old Male.

Singh J, Solanki P, Usmani K J Indian Assoc Pediatr Surg. 2024; 29(1):75-77.

PMID: 38405254 PMC: 10883179. DOI: 10.4103/jiaps.jiaps_163_23.

Successful endoscopic sclerotherapy with bile duct stenting for a vascular malformation neighboring the duodenal papilla in blue rubber bleb nevus syndrome.

Unoura S, Toya Y, Kasugai S, Kumei T, Yamazato M, Sasaki Y DEN Open. 2022; 2(1):e113.

PMID: 35873521 PMC: 9302048. DOI: 10.1002/deo2.113.

Characteristics and Treatment Outcomes of Small-bowel Angioectasia in Systemic Sclerosis Patients: A Retrospective Observational Study.

Iio S, Oka S, Sumioka A, Tsuboi A, Tanaka H, Yamashita K Intern Med. 2021; 61(5):615-622.

PMID: 34433725 PMC: 8943382. DOI: 10.2169/internalmedicine.8034-21.

Endoscopic treatment of blue rubber bleb nevus syndrome in a 4-year-old girl with long-term follow-up: A case report.

Marakhouski K, Sharafanovich E, Kolbik U, Sautin A, Nikalayeva K, Pataleta A World J Gastrointest Endosc. 2021; 13(3):90-96.

PMID: 33763189 PMC: 7958468. DOI: 10.4253/wjge.v13.i3.90.

References

Nobuhara Y, Onoda N, Fukai K, Hosomi N, Ishii M, Wakasa K . TIE2 gain-of-function mutation in a patient with pancreatic lymphangioma associated with blue rubber-bleb nevus syndrome: report of a case. Surg Today. 2006; 36(3):283-6. DOI: 10.1007/s00595-005-3138-9. View

Gallo S, McClave S . Blue rubber bleb nevus syndrome: gastrointestinal involvement and its endoscopic presentation. Gastrointest Endosc. 1992; 38(1):72-6. DOI: 10.1016/s0016-5107(92)70339-3. View

Hasosah M, Abdul-Wahab A, Bin-Yahab S, Al-Rabeaah A, Rimawi M, Eyoni Y . Blue rubber bleb nevus syndrome: extensive small bowel vascular lesions responsible for gastrointestinal bleeding. J Paediatr Child Health. 2009; 46(1-2):63-5. DOI: 10.1111/j.1440-1754.2009.01619.x. View

Ng W, Wong Y . Blue rubber bleb nevus syndrome: more lessons to be learnt. Eur J Pediatr Surg. 2007; 17(3):221-2. DOI: 10.1055/s-2007-965392. View

Deng Z, Xu C, Chen S . Diagnosis and treatment of blue rubber bleb nevus syndrome in children. World J Pediatr. 2008; 4(1):70-3. DOI: 10.1007/s12519-008-0015-9. View