Endotipsitis: A Case Report with a Literature Review on an Emerging Prosthetic Related Infection

Overview

Journal World J Hepatol

Publisher Baishideng Publishing Group

Specialty Gastroenterology

Date 2015 Apr 14

PMID 25866608

Citations 9

Authors

Annalan Md Navaratnam

Matthew Grant

David B Banach

Affiliations

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Abstract

Aim: To investigate the etiology and management of a poorly understood complication of transjugular intrahepatic portosystemic shunt; "endotipsitis".

Methods: A MEDLINE database search was carried out, reviewing all papers with specific words in the title or abstract, and excluding appropriately. Of 283 papers that were reviewed, 22 papers reporting 53 cases in total were included in the analyses.

Results: No predominant etiology for endotipsitis was identified, but gram-positive organisms were more common among early-onset infections (P < 0.01). A higher mortality rate was associated with Staphylococcus aureus and Candida spp infections (P < 0.01). There was no trend in choice of antibiotic based on the microorganisms isolated and treatment varied from the guidelines of other vegetative prosthetic infections. In endotipsitis "high risk" organisms have been identified, emphasizing the importance of ensuring optimal antimicrobial therapy and adjunctive management strategies.

Conclusion: Higher mortality rate was associated with Staphylococcus aureus and Candida spp infections. A prospective multicenter trial is needed before specific treatment can be recommended.

Citing Articles

Late polymicrobial transjugular intrahepatic portosystemic shunt infection in a liver transplant patient: A case report.

Perez I, Haskal Z, Hogan J, Argo C World J Hepatol. 2022; 14(4):846-853.

PMID: 35646273 PMC: 9099098. DOI: 10.4254/wjh.v14.i4.846.

Endotipsitis: An Underdiagnosed Complication of Transjugular Intrahepatic Portosystemic Shunts.

Niyas V, Keri V, Kumar P J Clin Exp Hepatol. 2022; 12(1):222-224.

PMID: 35068804 PMC: 8766577. DOI: 10.1016/j.jceh.2021.02.009.

North American Practice-Based Recommendations for Transjugular Intrahepatic Portosystemic Shunts in Portal Hypertension.

Boike J, Thornburg B, Asrani S, Fallon M, Fortune B, Izzy M Clin Gastroenterol Hepatol. 2021; 20(8):1636-1662.e36.

PMID: 34274511 PMC: 8760361. DOI: 10.1016/j.cgh.2021.07.018.

Endotipsitis: a rare case of endovascular infection with ESBL .

Schwartz A, Garg A, Statz G, Smock J BMJ Case Rep. 2020; 13(4).

PMID: 32345585 PMC: 7213698. DOI: 10.1136/bcr-2019-233972.

Transhepatic Revision of Occluded Transjugular Intrahepatic Portosystemic Shunt Complicated by Endotipsitis.

Darrow A, Gaba R, Lokken R Semin Intervent Radiol. 2019; 35(5):492-496.

PMID: 30728666 PMC: 6363548. DOI: 10.1055/s-0038-1676092.

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