Genomic Characterization of EmsB Microsatellite Loci in Echinococcus Multilocularis
Overview
Genetics
Infectious Diseases
Affiliations
EmsB is a molecular marker applied to Echinococcus multilocularis genotyping studies. This marker has largely been used to investigate the epidemiology of the parasite in different endemic foci. The present study has lifted the veil on the genetic structure of this microsatellite. By in silico analysis on the E. multilocularis genome the microsatellite was described in about 40 copies on the chromosome 5 of the parasite. Similar structure was found in the relative parasite Echinococcus granulosus, where the microsatellite was firstly described. The present study completes the first investigations made on the EmsB microsatellite origins and confirms the reliability of this highly discriminant molecular marker.
Assessment of the Genetic Diversity of from Copro-Isolated Eggs.
Knapp J, Malik Da Silva A, Courquet S, Millon L Pathogens. 2021; 10(10).
PMID: 34684245 PMC: 8541330. DOI: 10.3390/pathogens10101296.
Herzig M, Maksimov P, Staubach C, Romig T, Knapp J, Gottstein B Parasit Vectors. 2021; 14(1):535.
PMID: 34649615 PMC: 8518320. DOI: 10.1186/s13071-021-05038-0.
Umhang G, Knapp J, Wassermann M, Bastid V, de Garam C, Boue F Front Vet Sci. 2021; 7:620722.
PMID: 33521093 PMC: 7843918. DOI: 10.3389/fvets.2020.620722.
Mrad S, Oudni-Mrad M, Bastid V, Bournez L, Mosbahi S, Nouri A Pathogens. 2020; 9(6).
PMID: 32516904 PMC: 7350307. DOI: 10.3390/pathogens9060444.
Genotyping in Human Alveolar Echinococcosis Patients: An EmsB Microsatellite Analysis.
Knapp J, Gottstein B, Bretagne S, Bart J, Umhang G, Richou C Pathogens. 2020; 9(4).
PMID: 32295095 PMC: 7238142. DOI: 10.3390/pathogens9040282.