Atypical Early Aspergillus Endocarditis Post Prosthetic Mitral Valve Repair: a Case Report
Overview
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A 64-year-old female operated 1 month previous for mitral valve repair presented with acute respiratory distress and dyspnea. Echocardiography showed large echogenic valvular mass measuring 2.3 × 1.3 cm with severe mitral regurgitation and dehiscence of the mitral ring posteriorly. The mass was attached subvalvularly to the ventricular septal-free wall and eroding through it, which required complete aggressive dissection of the infected tissues. Diagnosis was confirmed after resection of the valve by multiple negative blood cultures and positive valvular tissue for Aspergillus fumigatus endocarditis. She was treated with high dose of voriconazole for 3 months. Her postoperative period was complicated by acute-on-chronic renal failure. She responded very well to the management.
Yassin Z, Hajsadeghi S, Shavazi M, Fattahi M, Ahmadzadeh K, Farid A J Med Case Rep. 2023; 17(1):519.
PMID: 38110954 PMC: 10729585. DOI: 10.1186/s13256-023-04252-x.
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Fattahi A, Sayyahfar S, Lotfali E, Ghasemi R, Mortezaeian H Curr Med Mycol. 2021; 6(4):70-74.
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Potential benefit of combination antifungal therapy in endocarditis.
Lennard K, Bannan A, Grant P, Post J BMJ Case Rep. 2020; 13(6).
PMID: 32532907 PMC: 7295381. DOI: 10.1136/bcr-2019-234008.
Rapid Fulminant Case of Aspergillus Prosthetic Valve Endocarditis.
Ortega-Loubon C, Fernandez-Molina M, Tobar-Ruiz J, Arce-Ramos N, Fulquet-Carreras E Cureus. 2017; 9(9):e1652.
PMID: 29142800 PMC: 5669520. DOI: 10.7759/cureus.1652.
Aspergillosis of the Heart and Lung and Review of Published Reports on Fungal Endocarditis.
Sulik-Tyszka B, Kacprzyk P, Madry K, Ziarkiewicz-Wroblewska B, JEdrzejczak W, Wroblewska M Mycopathologia. 2016; 181(7-8):583-8.
PMID: 27245170 PMC: 4937097. DOI: 10.1007/s11046-016-0012-9.