Factors Influencing the Dosimetry for High-intensity Focused Ultrasound Ablation of Uterine Fibroids: a Retrospective Study

Overview

Journal Medicine (Baltimore)

Specialty General Medicine

Date 2015 Apr 4

PMID 25837756

Citations 18

Authors

Song Peng

Lian Zhang

Liang Hu

Jinyun Chen

Jin Ju

Xi Wang

Rong Zhang

Zhibiao Wang

Wenzhi Chen

Affiliations

Soon will be listed here.

Abstract

The aim of this article is to analyze factors affecting sonication dose and build a dosimetry model of high-intensity focused ultrasound (HIFU) ablation for uterine fibroids. Four hundred and three patients with symptomatic uterine fibroids who underwent HIFU were retrospectively analyzed. The energy efficiency factor (EEF) was set as dependent variable, and the factors possibly affecting sonication dose included age, body mass index, size of uterine fibroid, abdominal wall thickness, the distance from uterine fibroid dorsal side to sacrum, the distance from uterine fibroid ventral side to skin, location of uterus, location of uterine fibroids, type of uterine fibroids, abdominal wall scar, signal intensity on T2-weighted imaging (T2WI), and enhancement type on T1-weighted imaging (T1WI) were set as predictors to build a multiple regression model. The size of uterine fibroid, distance from fibroid ventral side to skin, location of uterus, location of uterine fibroids, type of uterine fibroids, signal intensity on T2WI, and enhancement type on T1WI had a linear correlation with EEF. The distance from fibroid ventral side to skin, enhancement type on T1WI, size of uterine fibroid, and signal intensity on T2WI were eventually incorporated into the dosimetry model. The distance from fibroid ventral side to skin, enhancement type on T1WI, size of uterine fibroid, and signal intensity on T2WI can be used as dosimetric predictors for HIFU for uterine fibroids.

Citing Articles

Value of a combined magnetic resonance-enhanced and diffusion-weighted imaging dual-sequence radiomics model in predicting the efficacy of high-intensity focused ultrasound ablation for uterine fibroids.

Huang X, Shen L, Liu Y, Li Q, Bai S, Wang F BMC Med Imaging. 2025; 25(1):53.

PMID: 39962435 PMC: 11834504. DOI: 10.1186/s12880-025-01593-5.

The value of multi-parameter radiomics combined with imaging features in predicting the therapeutic efficacy of HIFU treatment for uterine fibroids.

Shen L, Huang X, Liu Y, Li Q, Bai S, Wang F Front Oncol. 2024; 14:1499387.

PMID: 39634270 PMC: 11614730. DOI: 10.3389/fonc.2024.1499387.

Ultrasound-guided high-intensity focused ultrasound for symptomatic uterine fibroids: clinical outcome of two European centers.

Dohmen S, Recker F, Ivanova Y, Strunk H, Tonguc T, Ramig O Eur Radiol. 2024; .

PMID: 39613955 DOI: 10.1007/s00330-024-11230-4.

High-intensity focused ultrasound for endometrial ablation in adenomyosis: a clinical study.

Wu S, Liu J, Liu X, Han Y Front Med (Lausanne). 2024; 11:1332080.

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