Hypertrophy of the Left Liver in Patients with Large Tumors in the Right Liver

Overview

Journal World J Surg

Publisher Wiley

Specialty General Surgery

Date 2015 Mar 28

PMID 25813823

Authors

Yoshimi Nakayama

Yoichi Ishizaki

Jiro Yoshimoto

Hiroyuki Sugo

Hiroshi Imamura

Seiji Kawasaki

Affiliations

Soon will be listed here.

Abstract

Background: It has been speculated that, when right-sided major hepatectomy (RSMH) is planned for patients with large tumors in the right liver, it may not lead to a marked decrease in normally functional hepatic mass.

Methods: We collected data for patients who had undergone RSMH for tumors more than 8 cm in diameter (n=50) and compared them with control patients who had undergone RSMH for tumors less than 5 cm in diameter (n=21).

Results: The ratio of the remnant left liver volume to the nontumorous liver volume (left liver ratio) in the patients with large tumors was significantly greater than that in the control group (50.0±12.8% vs. 40.2±8.3%, p=0.002). Left liver ratio was significantly correlated with tumor volume (p<0.001). Preoperative portal vein embolization was performed in only four of the 50 patients with large tumors. None of the patients with large tumors developed postoperative liver failure.

Conclusions: Left liver volume in patients with large tumors in the right liver was larger than usual, perhaps reducing the risk of postoperative liver insufficiency after RSMH.

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