» Articles » PMID: 25810918

A Nationwide Assessment of the Burden of Urinary Tract Infection Among Renal Transplant Recipients

Overview
Journal J Transplant
Publisher Wiley
Specialty General Surgery
Date 2015 Mar 27
PMID 25810918
Citations 2
Authors
Affiliations
Soon will be listed here.
Abstract

Objective. Evaluate the prevalence and outcomes of urinary tract infection (UTI) among renal transplant recipients. Methods. A secondary analysis of the Nationwide Inpatient Sample 2009-2011 was conducted. Survey-weighted multivariable regression analyses were used to examine the impact of UTI on transplant complications, total charges, and length of stay. Results. A total of 1,044 renal transplant recipients, representing a population estimate of 49,862, were included in the study. UTI was most common in transplant recipients with hypertension (53%) and prevalence was noted to be 28.2 and 65.9 cases per 1,000 for men and women, respectively. UTI increased the likelihood of transplant complications (182% for men, 169% for women). Total charges were 28% higher among men as compared to 22% among women with UTI. Such infection also increased the length of stay by 87% among men and 74% among women. Discussion. UTI in renal transplant recipients was associated with prolonged length of stay, total charges, and increased odds of transplant complications. Interventions to prevent UTI among such patients should be a priority area for future research and practice.

Citing Articles

Bacterial urinary tract infection among adult renal transplant recipients at St. Paul's hospital millennium medical college, Addis Ababa, Ethiopia.

Kiros T, Asrat D, Ayenew Z, Tsige E BMC Nephrol. 2019; 20(1):289.

PMID: 31366333 PMC: 6668100. DOI: 10.1186/s12882-019-1485-9.


Impact of Clostridium difficile infection among pneumonia and urinary tract infection hospitalizations: an analysis of the Nationwide Inpatient Sample.

Becerra M, Becerra B, Banta J, Safdar N BMC Infect Dis. 2015; 15:254.

PMID: 26126606 PMC: 4487835. DOI: 10.1186/s12879-015-0925-9.

References
1.
Ojo A, Hanson J, Meier-Kriesche H, Okechukwu C, Wolfe R, Leichtman A . Survival in recipients of marginal cadaveric donor kidneys compared with other recipients and wait-listed transplant candidates. J Am Soc Nephrol. 2001; 12(3):589-597. DOI: 10.1681/ASN.V123589. View

2.
Massie A, Kucirka L, Kuricka L, Segev D . Big data in organ transplantation: registries and administrative claims. Am J Transplant. 2014; 14(8):1723-30. PMC: 4387865. DOI: 10.1111/ajt.12777. View

3.
Kamath N, John G, Neelakantan N, Kirubakaran M, Jacob C . Acute graft pyelonephritis following renal transplantation. Transpl Infect Dis. 2006; 8(3):140-7. DOI: 10.1111/j.1399-3062.2006.00148.x. View

4.
Kang C, Chaudhry O, Halabi W, Nguyen V, Carmichael J, Mills S . Risk factors for postoperative urinary tract infection and urinary retention in patients undergoing surgery for colorectal cancer. Am Surg. 2012; 78(10):1100-4. View

5.
Dantas S, Kuboyama R, Mazzali M, Moretti M . Nosocomial infections in renal transplant patients: risk factors and treatment implications associated with urinary tract and surgical site infections. J Hosp Infect. 2006; 63(2):117-23. DOI: 10.1016/j.jhin.2005.10.018. View