Canaloplasty Versus Non-penetrating Deep Sclerectomy - a Prospective, Randomised Study of the Safety and Efficacy of Combined Cataract and Glaucoma Surgery; 12-month Follow-up

Overview

Journal Graefes Arch Clin Exp Ophthalmol

Specialty Ophthalmology

Date 2015 Mar 22

PMID 25795059

Citations 17

Authors

Marek Rekas

Anna Byszewska

Katarzyna Petz

Joanna Wierzbowska

Anselm Junemann

Affiliations

Soon will be listed here.

Abstract

Purpose: To compare outcomes of phaco-canaloplasty (PC) and phaco-non-penetrating deep sclerectomy (PDS) with a viscoelastic compound.

Methods: This study included 29 eyes after PC and 30 after PDS. Indications were uncontrolled primary open-angle glaucoma (POAG) and a cataract. Corrected distance visual acuity (CDVA), intraocular pressure (IOP), and number of medications were evaluated. Follow-up examinations were performed on days 1 and 7, and after 1, 3, 6, and 12 months. Complete and qualified success was an IOP ≤ 18 mmHg.

Results: At the 12-month follow-up, mean IOP decreased in the PC group from 19.0 ±6.9 mmHg to 12.6 ±2.7 mmHg, and in the PDS group, from 19.1 ±5.8 mmHg to 14.3 ±3.5 mmHg (P < 0.05). Both groups preoperatively and at 12 months showed no significant differences in IOP (P > 0.05). There was no statistically significant difference between the number of medications used (P > 0.05). Complete and qualified success rates for both groups were 79.0 % and 76.9 % (P = 0.701). The most frequent postoperative PC complication was hyphema (58.0 %); for PDS, bleb fibrosis was most frequent (26.7 %). No PC patients required postoperative management. PDS patients required postoperative interventions 58.7 % of the time, including a 5-fluorouracil (5-FU) injection (58.7 %), suture lysis (48.3 %), and needling (27.6 %).

Conclusions: Both PC and PDS lead to an effective decrease in IOP on a short-term follow-up basis and demonstrate similar efficacy and safety profiles. PDS patients required additional procedures including 5-FU injections, suture lysis, or needling. PC patients required no additional procedures.

Citing Articles

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Historical and Contemporary Debates in Schlemm's Canal-Based MIGS.

Chihara E, Hamanaka T J Clin Med. 2024; 13(16).

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Glaucoma Surgery and Ocular Blood Flow in Colour Doppler Imaging: Is There a Link?.

Zarzecki M, Obuchowska I, Ustymowicz A, Konopinska J Clin Ophthalmol. 2024; 18:49-60.

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Refractive astigmatism in phaco-canaloplasty vs phaco-non-penetrating deep sclerectomy.

Byszewska A, Rudowicz J, Lewczuk K, Jablonska J, Rekas M Sci Rep. 2022; 12(1):8604.

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Evaluation of the Efficacy and Safety of Canaloplasty and iStent Bypass Implantation in Patients with Open-Angle Glaucoma: A Review of the Literature.

Golaszewska K, Konopinska J, Obuchowska I J Clin Med. 2021; 10(21).

PMID: 34768400 PMC: 8584607. DOI: 10.3390/jcm10214881.

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