Influence of Implant Surface Topography on Primary Stability in a Standardized Osteoporosis Rabbit Model Study

Overview

Journal J Funct Biomater

Specialty Biomedical Engineering

Date 2015 Mar 21

PMID 25794350

Citations 11

Authors

Hiroshi Oue

Kazuya Doi

Yoshifumi Oki

Yusuke Makihara

Takayasu Kubo

Vittoria Perrotti

Adriano Piattelli

Yasumasa Akagawa

Kazuhiro Tsuga

Affiliations

Soon will be listed here.

Abstract

Evaluating primary stability is important to predict the prognosis of dental implant treatment. Primary stability is decreased in a low bone density site such as osteoporosis. However, it is difficult to apply in small animal and the effect of the different implant surface topography for the primary stability at low bone density site has not yet fully been investigated. The purpose of the present study was to evaluate the influence of implant surface topography on primary stability in a standardized osteoporosis animal model. Six rabbits underwent ovariectomy and administrated glucocorticoid to induce an osteoporosis model. Sham-operations were performed in additional six rabbits. Implants with machined or oxidized-surfaces were inserted into the femur epiphyses and insertion torque (IT) and implant stability quotient (ISQ) were measured. In sham model, the IT and ISQ did not differ significantly between the both implant. However, the IT value of oxidized-surface implant was significantly higher than that of the machined implant in the osteoporosis model. Meanwhile, ISQ did not significantly differ between the machined and oxidized-surfaced implants. In conclusion, the IT of implants is higher with rough than with smooth surfaces but that there are no differences in ISQ value between different surfaces in a standardized osteoporosis bone reduced rabbit model.

Citing Articles

Evaluation of Bone Density for Primary Implant Stability Using a Newly Designed Drill: An In Vitro Study on Polyurethane Bone Blocks.

Wakamatsu K, Doi K, Kobatake R, Oki Y, Tsuga K Clin Exp Dent Res. 2024; 10(6):e70048.

PMID: 39610027 PMC: 11604594. DOI: 10.1002/cre2.70048.

Investigation to Predict Primary Implant Stability Using Frictional Resistance Torque of Tap Drilling.

Wakamatsu K, Doi K, Kobatake R, Makihara Y, Oki Y, Tsuga K J Oral Maxillofac Res. 2023; 13(4):e1.

PMID: 36788798 PMC: 9902023. DOI: 10.5037/jomr.2022.13401.

Role of animal models in biomedical research: a review.

Mukherjee P, Roy S, Ghosh D, Nandi S Lab Anim Res. 2022; 38(1):18.

PMID: 35778730 PMC: 9247923. DOI: 10.1186/s42826-022-00128-1.

Histological and histomorphometric aspects of continual intermittent parathyroid hormone administration on osseointegration in osteoporosis rabbit model.

Oki Y, Doi K, Kobatake R, Makihara Y, Morita K, Kubo T PLoS One. 2022; 17(6):e0269040.

PMID: 35675357 PMC: 9176794. DOI: 10.1371/journal.pone.0269040.

Morphological Evaluation of Bone by CT to Determine Primary Stability-Clinical Study.

Takechi M, Ishioka Y, Ninomiya Y, Ono S, Tada M, Nakagawa T Materials (Basel). 2020; 13(11).

PMID: 32521622 PMC: 7321591. DOI: 10.3390/ma13112605.

References

Morita K, Doi K, Oue H, Kajihara S, Hayashi K, Akagawa Y . Influence of formalin fixation on the implant stability quotient and mechanical characteristics of bone. Br J Oral Maxillofac Surg. 2012; 51(6):550-4. DOI: 10.1016/j.bjoms.2012.08.009. View

Becker W, Hujoel P, Becker B, Willingham H . Osteoporosis and implant failure: an exploratory case-control study. J Periodontol. 2000; 71(4):625-31. DOI: 10.1902/jop.2000.71.4.625. View

Almagro M, Roman-Blas J, Bellido M, Castaneda S, Cortez R, Herrero-Beaumont G . PTH [1-34] enhances bone response around titanium implants in a rabbit model of osteoporosis. Clin Oral Implants Res. 2012; 24(9):1027-34. DOI: 10.1111/j.1600-0501.2012.02495.x. View

Shibli J, Aguiar K, Melo L, Davila S, Zenobio E, Faveri M . Histological comparison between implants retrieved from patients with and without osteoporosis. Int J Oral Maxillofac Surg. 2008; 37(4):321-7. DOI: 10.1016/j.ijom.2007.11.019. View

Degidi M, Piattelli A, Shibli J, Perrotti V, Iezzi G . Bone formation around immediately loaded and submerged dental implants with a modified sandblasted and acid-etched surface after 4 and 8 weeks: a human histologic and histomorphometric analysis. Int J Oral Maxillofac Implants. 2009; 24(5):896-901. View

Castaneda S, Largo R, Calvo E, Rodriguez-Salvanes F, Marcos M, Diaz-Curiel M . Bone mineral measurements of subchondral and trabecular bone in healthy and osteoporotic rabbits. Skeletal Radiol. 2005; 35(1):34-41. DOI: 10.1007/s00256-005-0022-z. View

da Cunha H, Francischone C, Filho H, de Oliveira R . A comparison between cutting torque and resonance frequency in the assessment of primary stability and final torque capacity of standard and TiUnite single-tooth implants under immediate loading. Int J Oral Maxillofac Implants. 2004; 19(4):578-85. View

Suito H, Tomotake Y, Watanabe M, Nagao D, Ishida Y, Ichikawa T . Survival of immediate implant restoration: a retrospective study through 9-year-observation. J Prosthodont Res. 2011; 55(3):141-5. DOI: 10.1016/j.jpor.2010.10.004. View

Doi K, Kubo T, Takeshita R, Kajihara S, Kato S, Kawazoe Y . Inorganic polyphosphate adsorbed onto hydroxyapatite for guided bone regeneration: an animal study. Dent Mater J. 2014; 33(2):179-86. DOI: 10.4012/dmj.2013-275. View

10.

Johansson B, Back T, Hirsch J . Cutting torque measurements in conjunction with implant placement in grafted and nongrafted maxillas as an objective evaluation of bone density: a possible method for identifying early implant failures?. Clin Implant Dent Relat Res. 2004; 6(1):9-15. DOI: 10.1111/j.1708-8208.2004.tb00022.x. View

11.

Piattelli M, Scarano A, Paolantonio M, Iezzi G, Petrone G, Piattelli A . Bone response to machined and resorbable blast material titanium implants: an experimental study in rabbits. J Oral Implantol. 2002; 28(1):2-8. DOI: 10.1563/1548-1336(2002)028<0002:BRTMAR>2.3.CO;2. View

12.

Al-Nawas B, Wagner W, Grotz K . Insertion torque and resonance frequency analysis of dental implant systems in an animal model with loaded implants. Int J Oral Maxillofac Implants. 2006; 21(5):726-32. View

13.

Turner R, Maran A, Lotinun S, Hefferan T, Evans G, Zhang M . Animal models for osteoporosis. Rev Endocr Metab Disord. 2001; 2(1):117-27. DOI: 10.1023/a:1010067326811. View

14.

Jemt T, Lekholm U . Implant treatment in edentulous maxillae: a 5-year follow-up report on patients with different degrees of jaw resorption. Int J Oral Maxillofac Implants. 1995; 10(3):303-11. View

15.

Iezzi G, Scarano A, Di Stefano D, Arosio P, Doi K, Ricci L . Correlation between the bone density recorded by a computerized implant motor and by a histomorphometric analysis: a preliminary in vitro study on bovine ribs. Clin Implant Dent Relat Res. 2013; 17 Suppl 1:e35-44. DOI: 10.1111/cid.12121. View

16.

Doi K, Kajihara S, Morita K, Makihara Y, Okada S, Akagawa Y . The influence of fixation in formalin on the measurement of stability of implants using resonance frequency analysis and Periotest M®: a study in a dog. Br J Oral Maxillofac Surg. 2013; 52(1):29-33. DOI: 10.1016/j.bjoms.2013.02.007. View

17.

Friberg B, Sennerby L, Linden B, Grondahl K, Lekholm U . Stability measurements of one-stage Brånemark implants during healing in mandibles. A clinical resonance frequency analysis study. Int J Oral Maxillofac Surg. 1999; 28(4):266-72. View

18.

Ostman P, Hellman M, Wendelhag I, Sennerby L . Resonance frequency analysis measurements of implants at placement surgery. Int J Prosthodont. 2006; 19(1):77-83. View

19.

Scarano A, Degidi M, Iezzi G, Petrone G, Piattelli A . Correlation between implant stability quotient and bone-implant contact: a retrospective histological and histomorphometrical study of seven titanium implants retrieved from humans. Clin Implant Dent Relat Res. 2006; 8(4):218-22. DOI: 10.1111/j.1708-8208.2006.00022.x. View

20.

Wennerberg A, Albrektsson T . On implant surfaces: a review of current knowledge and opinions. Int J Oral Maxillofac Implants. 2010; 25(1):63-74. View