Application of Bladder Acellular Matrix in Urinary Bladder Regeneration: the State of the Art and Future Directions

Overview

Journal Biomed Res Int

Publisher Wiley

Specialties Biomedical Engineering
Biotechnology
General Medicine

Date 2015 Mar 21

PMID 25793199

Citations 21

Authors

Marta Pokrywczynska

Iga Gubanska

Gerard Drewa

Tomasz Drewa

Affiliations

Soon will be listed here.

Abstract

Construction of the urinary bladder de novo using tissue engineering technologies is the "holy grail" of reconstructive urology. The search for the ideal biomaterial for urinary bladder reconstruction has been ongoing for decades. One of the most promising biomaterials for this purpose seems to be bladder acellular matrix (BAM). In this review we determine the most important factors, which may affect biological and physical properties of BAM and its regeneration potential in tissue engineered urinary bladder. We also point out the directions in modification of BAM, which include incorporation of exogenous growth factors into the BAM structure. Finally, we discuss the results of the urinary bladder regeneration with cell seeded BAM.

Citing Articles

Bladder Reconstruction in Cats Using In-Body Tissue Architecture (iBTA)-Induced Biosheet.

Fujita N, Sugiyama F, Tsuboi M, Nakamura H, Nishimura R, Nakayama Y Bioengineering (Basel). 2024; 11(6).

PMID: 38927851 PMC: 11200650. DOI: 10.3390/bioengineering11060615.

Tissue engineering in reconstructive urology-The current status and critical insights to set future directions-critical review.

Lawkowska K, Rosenbaum C, Petrasz P, Kluth L, Koper K, Drewa T Front Bioeng Biotechnol. 2023; 10:1040987.

PMID: 36950181 PMC: 10026841. DOI: 10.3389/fbioe.2022.1040987.

[Effects of porcine urinary bladder matrix on motility and polarization of bone marrow-derived macrophages in mice].

Tang X, Liu C, Chu G, Li X, Hu K, Zhao P Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2023; 39(1):25-34.

PMID: 36740423 PMC: 11630205. DOI: 10.3760/cma.j.cn501225-20220516-00187.

Bladder Acellular Matrix Prepared by a Self-Designed Perfusion System and Adipose-Derived Stem Cells to Promote Bladder Tissue Regeneration.

Xiao S, Wang P, Zhao J, Ling Z, An Z, Fu Z Front Bioeng Biotechnol. 2022; 10:794603.

PMID: 35814010 PMC: 9257038. DOI: 10.3389/fbioe.2022.794603.

Construction of Tissue-Engineered Bladder Scaffolds with Composite Biomaterials.

Li W, Qi N, Guo T, Wang C, Huang Z, Du Z Polymers (Basel). 2022; 14(13).

PMID: 35808700 PMC: 9269300. DOI: 10.3390/polym14132654.

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