Appearance and Disappearance of Chronic Myeloid Leukemia (CML) in Patient with Chronic Lymphocytic Leukemia (CLL)

Overview

Journal Int J Hematol Oncol Stem Cell Res

Specialty Hematology

Date 2015 Mar 17

PMID 25774268

Citations 1

Authors

Mehrdad Payandeh

Edris Sadeghi

Reza Khodarahmi

Masoud Sadeghi

Affiliations

Soon will be listed here.

Abstract

Chronic lymphocytic leukemia (CLL) and chronic myeloid leukemia (CML) are the most common leukemias of the elderly (>43 year). However, the sequential occurrence of CML followed by CLL in the same patient is extremely rare. In our report, a 52-year-old female was diagnosed with CLL (type of bone marrow (BM) infiltration was nodular and interstitial) and was treated with chlorambucil. 64 months after the diagnosis of CLL, she developed CML. She was treated with imatinib (400mg/day). After a few months, signs of CML were disappeared and CLL became dominant. This is first reported case.

Citing Articles

A Rare Case of an Elderly Male with Progression to Chronic Myeloid Leukaemia Secondary to Chronic Lymphocytic Leukaemia.

Saowapa S, Pangkanon W, Adu Y, Chaisrimaneepan N, Bernal D, Polpichai N Eur J Case Rep Intern Med. 2024; 11(4):004297.

PMID: 38584899 PMC: 10997395. DOI: 10.12890/2024_004297.

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