Sentinel Lymph Node Biopsy Using Computed Tomographic Lymphography in Patients with Early Tongue Cancer

Overview

Journal Acta Otolaryngol

Specialty Otorhinolaryngology

Date 2015 Mar 13

PMID 25761497

Citations 13

Authors

Kohei Honda

Koich Ishiyama

Shinsuke Suzuki

Eigo Oumi

Teruyuki Sato

Yohei Kawasaki

Hidekazu Saito

Kazuo Ishikawa

Affiliations

Soon will be listed here.

Abstract

Conclusions: Because computed tomography (CT) lymphography provides preoperative images of anatomic relationships between a tumor, its associated lymph vessels, and the sentinel lymph node (SLN), it may aid in directing the SLN biopsy for management of early tongue cancer.

Objectives: SLN biopsy using a radioisotope (RI) generally has been performed in head and neck cancer. However, this method can be performed only at institutions that are licenced for its use. In this study, we evaluated the utility of performing SLN biopsy in patients with early tongue cancer using the newly developed technique of CT lymphography.

Methods: Enrolled in this study were 31 patients with T1N0 or T2N0 tongue cancer. CT images were obtained before and after injection of iopamidol into the peritumoral region and the SLN was identified as the first enhanced lymph node. SLN biopsy was performed using CT lymphographic guidance combined with blue dye injection.

Results: The SLN was detected by CT lymphography in 28 cases (90.3%). By intraoperative frozen section examination, metastases to SLNs were found in 4 (14.3%) (T1N0, 1 patient; T2N0, 3 patients) of the 28 patients. Of these four, SLN micrometastases were found in one patient.

Citing Articles

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CT Lymphography Using Lipiodol for Sentinel Lymph Node Biopsy in Early-Stage Oral Cancer.

Mahieu R, Donders D, Dankbaar J, de Bree R, de Keizer B J Clin Med. 2022; 11(17).

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Application of preoperative computed tomographic lymphography for precise sentinel lymph node biopsy in breast cancer patients.

Wen S, Liang Y, Kong X, Liu B, Ma T, Zhou Y BMC Surg. 2021; 21(1):187.

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Novel Diagnostic Approaches for Assessment of the Clinically Negative Neck in Head and Neck Cancer Patients.

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MR lymphography with superparamagnetic iron oxide for sentinel lymph node mapping of N0 early oral cancer: A pilot study.

Sugiyama S, Iwai T, Baba J, Oguri S, Izumi T, Sekino M Dentomaxillofac Radiol. 2020; 50(4):20200333.

PMID: 33180632 PMC: 8077995. DOI: 10.1259/dmfr.20200333.

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