Computed Tomography and Magnetic Resonance Imaging of Thoracic Chordoma in a Bengal Tiger (Panthera Tigris Tigris)

Overview

Journal J Vet Med Sci

Specialty Veterinary Medicine

Date 2015 Mar 11

PMID 25754498

Authors

Toshie Iseri

Junichiro Shimizu

Hideo Akiyoshi

Kayo Kusuda

Akiyoshi Hayashi

Keiichiro Mie

Takeshi Izawa

Mitsuru Kuwamura

Jyoji Yamate

Yuka Fujimoto

Fumihito Ohashi

Affiliations

Soon will be listed here.

Abstract

A Bengal tiger was presented for evaluation of weakness, ataxia and inappetance. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed a mass extending from the T7-8 vertebral body to the left rib and compressing the spinal cord. On CT, the bone destruction and sequestrum were shown. On MRI, the multilobulated mass appeared hypo- to isointense in T1-weighted and hyperintense in T2-weighted images. The tiger died after imaging, most likely from renal failure. Chordoma without metastasis was diagnosed on necropsy. The imaging characteristics were similar to those found in chordoma in humans. This report describes the use of CT and MRI in an exotic species.

References

Kishimoto R, Omatsu T, Hasegawa A, Imai R, Kandatsu S, Kamada T . Imaging characteristics of metastatic chordoma. Jpn J Radiol. 2012; 30(6):509-16. DOI: 10.1007/s11604-012-0086-3. View

Stigen O, Ottesen N, Gamlem H, Akesson C . Cervical chondroid chordoma in a standard dachshund: a case report. Acta Vet Scand. 2011; 53:55. PMC: 3224775. DOI: 10.1186/1751-0147-53-55. View

Chua H, Horrigan M, McIntosh E, Bellomo R . Extended renal outcomes with use of iodixanol versus iohexol after coronary angiography. Biomed Res Int. 2014; 2014:506479. PMC: 4142278. DOI: 10.1155/2014/506479. View

Pease A, Berry C, Mott J, Peck J, Calderwood Mays M, Hinton D . Radiographic, computed tomographic and histopathologic appearance of a presumed spinal chordoma in a dog. Vet Radiol Ultrasound. 2002; 43(4):338-42. DOI: 10.1111/j.1740-8261.2002.tb01014.x. View

Munday J, Brown C, Weiss R . Coccygeal chordoma in a dog. J Vet Diagn Invest. 2003; 15(3):285-8. DOI: 10.1177/104063870301500312. View

Erdem E, Angtuaco E, Van Hemert R, Park J, Al-Mefty O . Comprehensive review of intracranial chordoma. Radiographics. 2003; 23(4):995-1009. DOI: 10.1148/rg.234025176. View

Hadlow W . Vertebral chordoma in two ranch mink. Vet Pathol. 1984; 21(5):533-6. DOI: 10.1177/030098588402100516. View

Seal U, Armstrong D, Simmons L . Yohimbine hydrochloride reversal of ketamine hydrochloride and xylazine hydrochloride immobilization of Bengal tigers and effects on hematology and serum chemistries. J Wildl Dis. 1987; 23(2):296-300. DOI: 10.7589/0090-3558-23.2.296. View

Stefanski S, Elwell M, Mitsumori K, Yoshitomi K, Dittrich K, Giles H . Chordomas in Fischer 344 rats. Vet Pathol. 1988; 25(1):42-7. DOI: 10.1177/030098588802500106. View

10.

Carpenter J, Stein B, King Jr N, Dayal Y, Moore F . Chordoma in a cat. J Am Vet Med Assoc. 1990; 197(2):240-2. View

11.

Ihle S, Kostolich M . Acute renal failure associated with contrast medium administration in a dog. J Am Vet Med Assoc. 1991; 199(7):899-901. View

12.

Dunn D, Harris R, Meis J, Sweet D . A histomorphologic and immunohistochemical study of chordoma in twenty ferrets (Mustela putorius furo). Vet Pathol. 1991; 28(6):467-73. DOI: 10.1177/030098589102800602. View

13.

Taki S, Kakuda K, Kakuma K, Yamashita R, Kosugi M, Annen Y . Posterior mediastinal chordoma: MR imaging findings. AJR Am J Roentgenol. 1996; 166(1):26-7. DOI: 10.2214/ajr.166.1.8571897. View

14.

Wippold 2nd F, Koeller K, Smirniotopoulos J . Clinical and imaging features of cervical chordoma. AJR Am J Roentgenol. 1999; 172(5):1423-6. DOI: 10.2214/ajr.172.5.10227531. View

15.

Woo G, Bak E, Lee Y, Nakayama H, Sasaki N, Doi K . Cervical chondroid chordoma in a Shetland sheep dog. J Comp Pathol. 2008; 138(4):218-23. DOI: 10.1016/j.jcpa.2007.12.004. View

16.

Uemura K, Shintani-Ishida K, Saka K, Nakajima M, Ikegaya H, Kikuchi Y . Biochemical blood markers and sampling sites in forensic autopsy. J Forensic Leg Med. 2008; 15(5):312-7. DOI: 10.1016/j.jflm.2007.12.003. View

17.

Gruber A, Kneissl S, Vidoni B, Url A . Cervical spinal chordoma with chondromatous component in a dog. Vet Pathol. 2008; 45(5):650-3. DOI: 10.1354/vp.45-5-650. View

18.

Yan Z, Yang B, Wang Z, Xian J, Li M . Primary chordoma in the nasal cavity and nasopharynx: CT and MR imaging findings. AJNR Am J Neuroradiol. 2009; 31(2):246-50. PMC: 7964161. DOI: 10.3174/ajnr.A1802. View

19.

Si M, Wang C, Ding X, Yuan F, Du L, Lu Y . Differentiation of primary chordoma, giant cell tumor and schwannoma of the sacrum by CT and MRI. Eur J Radiol. 2013; 82(12):2309-15. DOI: 10.1016/j.ejrad.2013.08.034. View