Elucidating the Links Between Endocrine Disruptors and Neurodevelopment

Overview

Journal Endocrinology

Publisher Oxford University Press

Specialty Endocrinology

Date 2015 Feb 26

PMID 25714811

Citations 72

Authors

Thaddeus T Schug

Ashley M Blawas

Kimberly Gray

Jerrold J Heindel

Cindy P Lawler

Affiliations

Soon will be listed here.

Abstract

Recent data indicate that approximately 12% of children in the United States are affected by neurodevelopmental disorders, including attention deficit hyperactivity disorder, learning disorders, intellectual disabilities, and autism spectrum disorders. Accumulating evidence indicates a multifactorial etiology for these disorders, with social, physical, genetic susceptibility, nutritional factors, and chemical toxicants acting together to influence risk. Exposure to endocrine-disrupting chemicals during the early stages of life can disrupt normal patterns of development and thus alter brain function and disease susceptibility later in life. This article highlights research efforts and pinpoints approaches that could shed light on the possible associations between environmental chemicals that act on the endocrine system and compromised neurodevelopmental outcomes.

Citing Articles

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Gestational exposure to environmental chemical mixtures and cognitive abilities in children: A pooled analysis of two North American birth cohorts.

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