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The Unacknowledged Impact of Urinary Schistosomiasis in Children: 5 Cases from Kumasi, Ghana

Overview
Journal Ghana Med J
Specialty General Medicine
Date 2015 Feb 25
PMID 25709140
Citations 8
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Abstract

Urinary schistosomiasis is a parasitic disease caused by Shistosoma haematobium. It is prevalent in several parts of Africa particularly in areas where there are large water bodies. In most affected communities, the condition is often accepted as normal since to them, all growing children pass blood in their urine and "grow out of it". Mass treatment of school children has been a regular exercise often undertaken by stake holders to decrease the disease burden and reduce transmission in selected communities. Urinary schistosomiasis can have devastating impact on the urinary tract which is often unacknowledged and unevaluated. Such omission could have implication for progressive renal damage which, if not detected and treated, could lead to end stage renal failure and death. We present five (5) cases of urinary schistosomiasis with severe obstructive uropathy seen at the paediatric nephrology/urology units of Komfo Anokye Teaching Hospital, Ghana. All five cases had some degree of anaemia and hypertension. Two of the five cases presented with end stage renal failure and died subsequently whilst two underwent successful surgery. One made a spontaneous recovery from the urinary obstruction though still has significant renal impairment. This potential devastating effect of urinary schistosomiasis on the kidneys calls for thorough evaluation and assessment of each confirmed case to include blood pressure measurement, full blood count, and ultrasonography of the urinary system. Mass screening programmes should be combined with portable ultrasonography of the kidneys, ureters and bladder.

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References
1.
Martinelli R, Noblat A, Brito E, Rocha H . Schistosoma mansoni-induced mesangiocapillary glomerulonephritis: influence of therapy. Kidney Int. 1989; 35(5):1227-33. DOI: 10.1038/ki.1989.114. View

2.
Tohon Z, Mainassara H, Garba A, Mahamane A, Bosque-Oliva E, Ibrahim M . Controlling schistosomiasis: significant decrease of anaemia prevalence one year after a single dose of praziquantel in Nigerian schoolchildren. PLoS Negl Trop Dis. 2008; 2(5):e241. PMC: 2386241. DOI: 10.1371/journal.pntd.0000241. View

3.
Sobh M, Moustafa F, Basta M, Deelder A, Ghoniem M . Schistosomal specific nephropathy leading to end-stage renal failure. Kidney Int. 1987; 31(4):1006-11. DOI: 10.1038/ki.1987.99. View

4.
Iarotski L, Davis A . The schistosomiasis problem in the world: results of a WHO questionnaire survey. Bull World Health Organ. 1981; 59(1):115-27. PMC: 2396036. View

5.
Lyons G . Schistosomiasis in north-western Ghana. Bull World Health Organ. 1974; 51(6):621-32. PMC: 2366268. View