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Hemodialysis Patients Profile at Dow University of Health Sciences, Karachi. Pakistan

Overview
Journal Pak J Med Sci
Specialty General Medicine
Date 2015 Feb 13
PMID 25674133
Citations 5
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Abstract

Objectives: To determine the frequency of diseases contributing to End Stage Renal Failure (ESRF) and to determine the frequency of seropositivity for hepatitis B and hepatitis C in our patients.

Methods: This is an observational study of two years duration from January 2012 till December 2013, done at Dow university of Health Sciences. Sample size is 189 by convenient method. Data collection is retrospective. Inclusion criteria includes all patients ever hemodialysed at DIMC with age 14 or above. Exclusion criteria is age below 14. Data maintained and analyzed on SPSS version 16. All categorical data in percentages and numeric data is given in frequencies and mean with Standard deviation.

Result: Total number of patients included in study were 189, Males were 94/189 (49.7%), females were 95/189 (50.3%), Male to female ratio was 0.98: 1.0. Mean age was 51.88+15.2, range was14-86 years. Patients started on Hemodialysis were found to have hypertension in 40.2%, both diabetes and hypertension was present in 42.8%, diabetes alone in 3.1% of patients as likely etiology of renal failure. Seropositivity for HBV was found 4/189(2.1%) and HCV in 31/189(16.4%) at initiation of Hemodialysis.

Conclusion: Hypertension alone is an important disease found in patients with renal failure as likely cause followed by diabetes. Hepatitis C positivity at start of hemodialysis is 16%.

Citing Articles

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Use of sofosbuvir based regimen in patients with end-stage renal disease and chronic hepatitis C; an open label, non-randomized, single arm, single center study from Pakistan.

Mandhwani R, Hanif F, Lail G, Hassan Luck N, Khalid M, Ul Haque M Gastroenterol Hepatol Bed Bench. 2020; 13(2):141-146.

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The epidemiology of hepatitis C virus in Pakistan: systematic review and meta-analyses.

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Epidemiology of hepatitis C virus among hemodialysis patients in the Middle East and North Africa: systematic syntheses, meta-analyses, and meta-regressions.

Harfouche M, Chemaitelly H, Mahmud S, Chaabna K, Kouyoumjian S, Al Kanaani Z Epidemiol Infect. 2017; 145(15):3243-3263.

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End Stage Renal Disease: Seroprevalence of Hepatitises B and C along with Associated Aetiology and Risk Factors in Children.

Shah S, Khan M, Alam M, Salim A, Hussain M, Altaf A J Trop Med. 2015; 2015:936094.

PMID: 26346273 PMC: 4541010. DOI: 10.1155/2015/936094.

References
1.
Anwar M, Rahman M, Hassan M, Iqbal M . Prevalence of active hepatitis C virus infections among general public of Lahore, Pakistan. Virol J. 2013; 10:351. PMC: 4029204. DOI: 10.1186/1743-422X-10-351. View

2.
Zafar J, Bhatti F, Akhtar N, Rasheed U, Bashir R, Humayun S . Prevalence and risk factors for diabetes mellitus in a selected urban population of a city in Punjab. J Pak Med Assoc. 2012; 61(1):40-7. View

3.
Jafar T, Jessani S, Jafary F, Ishaq M, Orakzai R, Orkazai R . General practitioners' approach to hypertension in urban Pakistan: disturbing trends in practice. Circulation. 2005; 111(10):1278-83. DOI: 10.1161/01.CIR.0000157698.78949.D7. View

4.
Masood C, Afzal W . Long-term complications of diabetes and co-morbidities contributing to atherosclerosis in diabetic population of Mirpur, Azad Kashmir. J Pak Med Assoc. 2014; 63(11):1383-6. View

5.
DiBonaventura M, Yuan Y, Lescrauwaet B, LItalien G, Liu G, Kamae I . Multicountry burden of chronic hepatitis C viral infection among those aware of their diagnosis: a patient survey. PLoS One. 2014; 9(1):e86070. PMC: 3897615. DOI: 10.1371/journal.pone.0086070. View