Life-threatening Anaphylactic Shock Due to Chlorhexidine on the Central Venous Catheter: a Case Series

Overview

Journal Int J Clin Exp Med

Specialty General Medicine

Date 2015 Feb 10

PMID 25664137

Citations 9

Authors

Meilin Weng

Minmin Zhu

Wankun Chen

Changhong Miao

Affiliations

Soon will be listed here.

Abstract

In this article, we report two life-threatening anaphylactic shocks by an antiseptic coated central venous catheter (CVC) within a 6-month period in our cancer center. Anaphylactic shock was preceded immediately after insertion of a central venous catheter (CVC) coated with silver sulphadiazine and chlorhexidine acetate (Blue FlexTip(®) ARROWg(+)ard Blue(®), 14Ga, Arrow International, Inc. USA). Though antiseptic coated CVC anaphylaxis has been reported in Japan, Europe and America, to our knowledge, this is first reported in China. We present these rare cases to remind clinicians about hypersensitivity to chlorhexidine that could potentially be life-threatening.

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