Quantitative Assessment of Physiological Cerebrospinal Fluid Flow in the Cervical Spinal Canal with 3.0T Phase-contrast Cine MRI

Overview

Journal Neural Regen Res

Date 2015 Feb 7

PMID 25657672

Authors

Hua Shang

Huaijun Liu

Leka Yan

Jianming Lei

Caixia Cui

Hui Li

Affiliations

Soon will be listed here.

Abstract

A total of 50 healthy volunteers aged between 18 and 54 years underwent phase-contrast cine MRI to assess cerebrospinal fluid flow characteristics in different regions of the vertebral canal. The results revealed that the cerebrospinal fluid peak flow velocity and peak flow rate in the systolic phase were significantly greater than those in the diastolic phase at the same level in the subarachnoid space of the cervical spinal canal. The ventral peak flow velocity and peak flow rate were significantly greater than the post-lateral peak flow velocity and flow rate, while there were no differences between left and right post-lateral subarachnoid peak velocity and flow rate. Moreover, there were no significant differences in peak flow velocity and peak flow rate between the systolic and diastolic phases, ventral, right post-lateral or left post-lateral peak flow velocity and peak flow rate at the same level in the subarachnoid space of the cervical spinal canal among different age groups (18-24, 25-34, 35-44, ≥ 45 years).

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