Effect of Hemodialysis on Visual Acuity, Intraocular Pressure, and Macular Thickness in Patients with Chronic Kidney Disease

Overview

Journal Clin Ophthalmol

Publisher Dove Medical Press

Specialty Ophthalmology

Date 2015 Feb 7

PMID 25657575

Citations 19

Authors

Elias Chelala

Ali Dirani

Ali Fadlallah

Elise Slim

Youssef Abdelmassih

Henry Fakhoury

Patrick Baz

Riad Bejjani

Affiliations

Soon will be listed here.

Abstract

Background: The aim of this study was to evaluate the effects of hemodialysis (HD) on visual acuity, intraocular pressure (IOP), and central foveal thickness (CFT) in patients with chronic kidney disease.

Materials And Methods: Forty-nine eyes from 49 chronic kidney-disease patients were analyzed. Causes of chronic kidney disease included diabetes mellitus (n=9 patients), hypertensive nephrosclerosis (n=15 patients), and other causes (n=25 patients). All patients underwent HD in the Dialysis Unit of Hôtel-Dieu de France Hospital. Best-corrected visual acuity, CFT, and IOP were evaluated before and after HD. CFT was measured with spectral domain optical coherence tomography, and IOP was measured with Goldmann applanation tonometry.

Results: Neither decimal best-corrected visual acuity (pre-HD 0.71±0.32, post-HD 0.72±0.31; P=0.877) nor CFT (pre-HD 251.39±39.29, post-HD 253.09±39.26; P=0.272) significantly changed after HD. However, mean IOP significantly decreased from 13.99±2.48 before HD to 12.65±2.41 mmHg after HD (P=0.001). IOP change was significantly correlated with serum albumin levels (P=0.008) and weight changes (P=0.047).

Conclusion: HD can affect various ocular parameters. This is particularly true of IOP, which decreases significantly following HD.

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Chow J, She P, Pee X, Wan Muda W, Bastion M PLoS One. 2022; 17(4):e0266607.

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