» Articles » PMID: 25647687

Refractory Esophageal Strictures: What to Do when Dilation Fails

Overview
Specialty Gastroenterology
Date 2015 Feb 4
PMID 25647687
Citations 43
Authors
Affiliations
Soon will be listed here.
Abstract

Benign esophageal strictures arise from a diversity of causes, for example esophagogastric reflux, esophageal resection, radiation therapy, ablative therapy, or the ingestion of a corrosive substance. Most strictures can be treated successfully with endoscopic dilation using bougies or balloons, with only a few complications. Nonetheless, approximately one third of patients develop recurrent symptoms after dilation within the first year. The majority of these patients are managed with repeat dilations, depending on their complexity. Dilation combined with intra lesional steroid injections can be considered for peptic strictures, while incisional therapy has been demonstrated to be effective for Schatzki rings and anastomotic strictures. When these therapeutic options do not resolve the stenosis, stent placement should be considered. Self bougienage can be proposed to a selected group of patients with a proximal stenosis. As a final step surgery is an option, but even then the risk of stricture formation at the anastomotic site remains. This chapter reviews refractory benign esophageal strictures and the treatment options that are currently available.

Citing Articles

Endoscopic incisional balloon dilation combined with anti-scarring agents for postoperative esophageal anastomotic strictures.

Kumagai K, Takada Y, Sugimoto A, Sakagami S, Akioka Y, Mitani R DEN Open. 2025; 5(1):e70062.

PMID: 39822949 PMC: 11736416. DOI: 10.1002/deo2.70062.


Development of a prognostic nomogram model for predicting outcomes in benign esophagogastric anastomotic stenosis treated with fluoroscopic balloon dilation.

Li X, Wang S, Ding X, Qi Y, Li X, Yin M Surg Endosc. 2025; 39(3):1583-1592.

PMID: 39762605 DOI: 10.1007/s00464-024-11497-0.


Optimal diameter of endoscopic dilatation in anastomotic stricture after esophagectomy.

Ryu D, Choi C, Kim S, Park S, Jang J, Kim W Surg Endosc. 2024; 38(12):7253-7260.

PMID: 39394374 DOI: 10.1007/s00464-024-11342-4.


When Stents Go Astray, We Find a Way: A Case Report on Retrieving a Migrated Esophageal Stent.

Venu V, Bakhshi G, Dutt A, Raichur A, Jaiswal N Cureus. 2024; 16(8):e67009.

PMID: 39280543 PMC: 11402437. DOI: 10.7759/cureus.67009.


Efficacy and safety of radial incision and cutting for nonsurgical refractory benign esophageal stricture.

Mitani Y, Hirohashi K, Tamaoki M, Yokoyama A, Katada C, Ueda A Endosc Int Open. 2024; 12(9):E1035-E1042.

PMID: 39263558 PMC: 11387040. DOI: 10.1055/a-2382-6213.


References
1.
Dzeletovic I, Fleischer D . Self-dilation for resistant, benign esophageal strictures. Am J Gastroenterol. 2010; 105(10):2142-3. DOI: 10.1038/ajg.2010.212. View

2.
Repici A, Hassan C, Sharma P, Conio M, Siersema P . Systematic review: the role of self-expanding plastic stents for benign oesophageal strictures. Aliment Pharmacol Ther. 2010; 31(12):1268-75. DOI: 10.1111/j.1365-2036.2010.04301.x. View

3.
Cerna M, Kocher M, Valek V, Aujesky R, Neoral C, Andrasina T . Covered biodegradable stent: new therapeutic option for the management of esophageal perforation or anastomotic leak. Cardiovasc Intervent Radiol. 2011; 34(6):1267-71. DOI: 10.1007/s00270-010-0059-9. View

4.
Camargo M, Lopes L, Grangeia T, Andreollo N, Brandalise N . [Use of corticosteroids after esophageal dilations on patients with corrosive stenosis: prospective, randomized and double-blind study]. Rev Assoc Med Bras (1992). 2003; 49(3):286-92. DOI: 10.1590/s0104-42302003000300033. View

5.
Boyce H . Dilation of difficult benign esophageal strictures. Am J Gastroenterol. 2005; 100(4):744-5. DOI: 10.1111/j.1572-0241.2005.41477.x. View