The Effects of Water Pipe Smoking on Hematological Parameters in Rats

Overview

Journal Int J Hematol Oncol Stem Cell Res

Specialty Hematology

Date 2015 Feb 3

PMID 25642307

Citations 7

Authors

Ebrahim Miri-Moghaddam

Ramazan Mirzaei

Mohammad-Reza Arab

Samaneh Kaikha

Affiliations

Soon will be listed here.

Abstract

Objectives: This study aimed to investigate the effect of water-pipe (WP) smoking on hematological parameters of Wistar rats.

Methods: Thirty-five young male rats (200-250 g) were randomly assigned to five groups (n=7). The control group was exposed to room air and the experimental groups were exposed to WP smoking, using a special apparatus designed to have the ability to keep the rats for 40 minutes every day for 4, 8, 12 and 12 weeks; moreover, one of the two groups of 12 weeks of WP exposer had four following weeks of rest. Blood samples were collected to evaluate red blood cell count, hemoglobin, hematocrit, white blood cell and platelet counts.

Results: The results showed that RBC count, Hb and Hct parameters were significantly higher in WP smoking rats than the control group (P< 0.001). We found that WBC counts insignificantly increased (P < 0.39) but Plt counts insignificantly decreased (P < 0.13) in WP smoking rats compared with control group.

Conclusion: The findings may help to raise awareness of tobacco smokers about the potential toxicities of WP; likewise, the results can be used by physicians and public health officials in tobacco prevention programs.

Citing Articles

Exposure to Waterpipe Smoke Disrupts Erythrocyte Homeostasis of BALB/c Mice.

Ferdous Z, Beegam S, Zaaba N, Nemmar A Biology (Basel). 2024; 13(6).

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Involvement of Sirtuins and Klotho in Cardioprotective Effects of Exercise Training Against Waterpipe Tobacco Smoking-Induced Heart Dysfunction.

Alavi S, Joukar S, Rostamzadeh F, Najafipour H, Darvishzadeh-Mahani F, Mortezaeizade A Front Physiol. 2021; 12:680005.

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Effects of Endurance Exercise Training on Cardiac Dysfunction Induced by Waterpipe Tobacco Smoking.

Nakhaee M, Joukar S, Zolfaghari M, Rostamzadeh F, Masoumi-Ardakani Y, Iranpour M Addict Health. 2019; 11(2):100-109.

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Water pipe smoking as a cause of secondary erythrocytosis.

Javorniczky N, Waller C, Pahl H, von Bubnoff N, Becker H Oxf Med Case Reports. 2019; 2019(5):omz027.

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Hookah smoking is strongly associated with diabetes mellitus, metabolic syndrome and obesity: a population-based study.

Saffar Soflaei S, Darroudi S, Tayefi M, Nosrati Tirkani A, Moohebati M, Ebrahimi M Diabetol Metab Syndr. 2018; 10:33.

PMID: 29713386 PMC: 5907743. DOI: 10.1186/s13098-018-0335-4.

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