» Articles » PMID: 25641003

Validation of Autism Spectrum Disorder Diagnoses in Large Healthcare Systems with Electronic Medical Records

Abstract

To identify factors associated with valid Autism Spectrum Disorder (ASD) diagnoses from electronic sources in large healthcare systems. We examined 1,272 charts from ASD diagnosed youth <18 years old. Expert reviewers classified diagnoses as confirmed, probable, possible, ruled out, or not enough information. A total of 845 were classified with 81% as a confirmed, probable, or possible ASD diagnosis. The predictors of valid ASD diagnoses were >2 diagnoses in the medical record (OR 2.94; 95% CI 2.03-4.25; p < 0.001) and being male (OR 1.51; 95% CI 1.05-2.17; p = 0.03). In large integrated healthcare settings, at least two diagnoses can be used to identify ASD patients for population-based research.

Citing Articles

Primary Care Autism Screening with the Parent's Observations of Social Interactions.

Carbone P, Campbell K, Villalobos M, Stuart A, Ellzey A, Stoddard G J Autism Dev Disord. 2025; .

PMID: 39985730 DOI: 10.1007/s10803-025-06759-2.


Maternal Prenatal Cannabis Use and Child Autism Spectrum Disorder.

Avalos L, Shenkute M, Alexeeff S, Oberman N, Croen L, Davignon M JAMA Netw Open. 2024; 7(10):e2440301.

PMID: 39422906 PMC: 11581557. DOI: 10.1001/jamanetworkopen.2024.40301.


Prenatal Exposure to Source-Specific Fine Particulate Matter and Autism Spectrum Disorder.

Luglio D, Kleeman M, Yu X, Lin J, Chow T, Martinez M Environ Sci Technol. 2024; 58(42):18566-18577.

PMID: 39392704 PMC: 11500427. DOI: 10.1021/acs.est.4c05563.


Decomposing the variance: The unique and shared associations of fine and ultrafine particulate matter exposed during pregnancy with child autism spectrum disorder.

Yu X, Kleeman M, Lin J, Chow T, Martinez M, Chen Z Sci Total Environ. 2024; 954:176609.

PMID: 39362545 PMC: 11567796. DOI: 10.1016/j.scitotenv.2024.176609.


Routine vaccine uptake in school-aged autistic and non-autistic youth: A linked database study.

Dodds L, Filliter C, Campbell L, MacDonald N, Shea S, Dube E Can J Public Health. 2024; 115(6):992-1001.

PMID: 39322915 PMC: 11644134. DOI: 10.17269/s41997-024-00937-y.


References
1.
. Prevalence of autism spectrum disorder among children aged 8 years - autism and developmental disabilities monitoring network, 11 sites, United States, 2010. MMWR Surveill Summ. 2014; 63(2):1-21. View

2.
. Prevalence of autism spectrum disorders--autism and developmental disabilities monitoring network, six sites, United States, 2000. MMWR Surveill Summ. 2007; 56(1):1-11. View

3.
Avchen R, Wiggins L, Devine O, Braun K, Rice C, Hobson N . Evaluation of a records-review surveillance system used to determine the prevalence of autism spectrum disorders. J Autism Dev Disord. 2010; 41(2):227-36. DOI: 10.1007/s10803-010-1050-7. View

4.
Lord C, Rutter M, Goode S, Heemsbergen J, Jordan H, Mawhood L . Autism diagnostic observation schedule: a standardized observation of communicative and social behavior. J Autism Dev Disord. 1989; 19(2):185-212. DOI: 10.1007/BF02211841. View

5.
Idring S, Rai D, Dal H, Dalman C, Sturm H, Zander E . Autism spectrum disorders in the Stockholm Youth Cohort: design, prevalence and validity. PLoS One. 2012; 7(7):e41280. PMC: 3401114. DOI: 10.1371/journal.pone.0041280. View