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Evaluation of Ebola Virus Inactivation Procedures for Plasmodium Falciparum Malaria Diagnostics

Overview
Journal J Clin Microbiol
Specialty Microbiology
Date 2015 Jan 30
PMID 25631810
Citations 10
Authors
Rachel Lau
Amanda Wang
Ann Chong-Kit
Filip Ralevski
Andrea K Boggild
Affiliations
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Abstract

Plasmodium falciparum malaria is highly endemic in the three most affected countries in the current epidemic of Ebola virus disease (EVD) in West Africa. As EVD and malaria are clinically indistinguishable, both remain part of the differential diagnosis of ill travelers from returning from areas of EVD transmission. We compared the performances of a rapid diagnostic test (BinaxNOW) and real-time PCR with P. falciparum-positive specimens before and after heat and Triton X-100 inactivation, and we documented no loss of sensitivity.

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