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Towards Co-evolution of Membrane Proteins and Metabolism

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Date 2015 Jan 24
PMID 25614291
Citations 6
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Abstract

Primordial metabolism co-evolved with the earliest membrane peptides to produce more environmentally fit progeny. Here, we map a continuous, evolutionary path that connects nascent biochemistry with simple, membrane-bound oligopeptides, ion channels and, further, membrane proteins capable of energy transduction and utilization of energy for active transport.

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