Facile Preparation of Nanogels Using Activated Ester Containing Polymers

Overview

Journal ACS Macro Lett

Publisher American Chemical Society

Specialty Chemistry

Date 2015 Jan 13

PMID 25580371

Citations 7

Authors

Jiaming Zhuang

Siriporn Jiwpanich

V D Deepak

S Thayumanavan

Affiliations

Soon will be listed here.

Abstract

A facile methodology to prepare water-dispersible nanogels based on pentafluorophenyl acrylate and polyethylene glycol methacrylate random copolymer and diamine cross-linkers has been developed. Cross-linking reaction was characterized by FTIR and F NMR. We show that those nanogels : () are water-dispersible; () can conveniently encapsulate lipophilic guest molecules; () can be prepared with different nanosizes; () are engineered to allow for surface decoration with additional functional groups.

Citing Articles

Structural Determinants of Stimuli-Responsiveness in Amphiphilic Macromolecular Nano-assemblies.

Liu H, Lu H, Alp Y, Wu R, Thayumanavan S Prog Polym Sci. 2024; 148.

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Nanogels as novel drug nanocarriers for CNS drug delivery.

Manimaran V, Nivetha R, Tamilanban T, Narayanan J, Vetriselvan S, Fuloria N Front Mol Biosci. 2023; 10:1232109.

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Thiol-Disulfide Exchange as a Route for Endosomal Escape of Polymeric Nanoparticles.

Kanjilal P, Dutta K, Thayumanavan S Angew Chem Int Ed Engl. 2022; 61(37):e202209227.

PMID: 35866880 PMC: 9452476. DOI: 10.1002/anie.202209227.

ROS-triggered degradable iron-chelating nanogels: Safely improving iron elimination in vivo.

Liu Z, Qiao J, Nagy T, Xiong M J Control Release. 2018; 283:84-93.

PMID: 29792889 PMC: 6035766. DOI: 10.1016/j.jconrel.2018.05.025.

Substituent Effects on the pH Sensitivity of Acetals and Ketals and Their Correlation with Encapsulation Stability in Polymeric Nanogels.

Liu B, Thayumanavan S J Am Chem Soc. 2017; 139(6):2306-2317.

PMID: 28106385 PMC: 5382500. DOI: 10.1021/jacs.6b11181.

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