Bone Physiology, Biomaterial and the Effect of Mechanical/Physical Microenvironment on MSC Osteogenesis: A Tribute to Shu Chien's 80th Birthday

Overview

Journal Cell Mol Bioeng

Publisher Springer

Specialty Biomedical Engineering

Date 2015 Jan 13

PMID 25580165

Citations 6

Authors

Xiaoling Liao

Shaoying Lu

Yue Zhuo

Christina Winter

Wenfeng Xu

Bo Li

Yingxiao Wang

Affiliations

Soon will be listed here.

Abstract

Professor Shu Chien is a world-renowned leader and founder of Bioengineering. In particular, he has made seminal contributions to advancing our systematic and insightful understanding of how cells perceive their physical/mechanical environment and coordinate cellular functions. In this review, as part of a tribute to Prof. Shu Chien's scientific achievement, we summarize the research progress in understanding the physiology of bone cells interacting with different mechanical/physical environments during bone tissue regeneration/repair. We first introduce the cellular composition of the bone tissue and the mechanism of the physiological bone regeneration/repair process. We then describe the properties and development of biomaterials for bone tissue engineering, followed by the highlighting of research progresses on the cellular response to mechanical environmental cues. Finally, several latest advancements in bone tissue regeneration and remaining challenges in the field are discussed for future research directions.

Citing Articles

Tamoxifen-Loaded Eudragit Nanoparticles: Quality by Design Approach for Optimization of Nanoparticles as Delivery System.

Khattak M, Iqbal Z, Nasir F, Neau S, Khan S, Hidayatullah T Pharmaceutics. 2023; 15(10).

PMID: 37896131 PMC: 10609841. DOI: 10.3390/pharmaceutics15102373.

Matrix stiffness, endothelial dysfunction and atherosclerosis.

Xu Z, Chen Y, Wang Y, Han W, Xu W, Liao X Mol Biol Rep. 2023; 50(8):7027-7041.

PMID: 37382775 DOI: 10.1007/s11033-023-08502-5.

Self-oxygenation of engineered living tissues orchestrates osteogenic commitment of mesenchymal stem cells.

Hassan S, Wang T, Shi K, Huang Y, Lopez M, Gan K Biomaterials. 2023; 300:122179.

PMID: 37315386 PMC: 10330822. DOI: 10.1016/j.biomaterials.2023.122179.

Rare earth smart nanomaterials for bone tissue engineering and implantology: Advances, challenges, and prospects.

Natarajan D, Ye Z, Wang L, Ge L, Pathak J Bioeng Transl Med. 2022; 7(1):e10262.

PMID: 35111954 PMC: 8780931. DOI: 10.1002/btm2.10262.

Scaffold Structural Microenvironmental Cues to Guide Tissue Regeneration in Bone Tissue Applications.

Chen X, Fan H, Deng X, Wu L, Yi T, Gu L Nanomaterials (Basel). 2018; 8(11).

PMID: 30469378 PMC: 6266401. DOI: 10.3390/nano8110960.

References

Caplan A . Mesenchymal stem cells. J Orthop Res. 1991; 9(5):641-50. DOI: 10.1002/jor.1100090504. View

Hench L, Thompson I . Twenty-first century challenges for biomaterials. J R Soc Interface. 2010; 7 Suppl 4:S379-91. PMC: 2943892. DOI: 10.1098/rsif.2010.0151.focus. View

Silva G, Coutinho O, Ducheyne P, Reis R . Materials in particulate form for tissue engineering. 2. Applications in bone. J Tissue Eng Regen Med. 2007; 1(2):97-109. DOI: 10.1002/term.1. View

Massberg S, Schaerli P, Knezevic-Maramica I, Kollnberger M, Tubo N, Moseman E . Immunosurveillance by hematopoietic progenitor cells trafficking through blood, lymph, and peripheral tissues. Cell. 2007; 131(5):994-1008. PMC: 2330270. DOI: 10.1016/j.cell.2007.09.047. View

Undale A, Westendorf J, Yaszemski M, Khosla S . Mesenchymal stem cells for bone repair and metabolic bone diseases. Mayo Clin Proc. 2009; 84(10):893-902. PMC: 2755808. DOI: 10.4065/84.10.893. View

Hench L . Biomaterials. Science. 1980; 208(4446):826-31. DOI: 10.1126/science.6246576. View

Schimming R, Schmelzeisen R . Tissue-engineered bone for maxillary sinus augmentation. J Oral Maxillofac Surg. 2004; 62(6):724-9. DOI: 10.1016/j.joms.2004.01.009. View

Oberdorster G, Oberdorster E, Oberdorster J . Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environ Health Perspect. 2005; 113(7):823-39. PMC: 1257642. DOI: 10.1289/ehp.7339. View

Nakamura T, Imai Y, Matsumoto T, Sato S, Takeuchi K, Igarashi K . Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts. Cell. 2007; 130(5):811-23. DOI: 10.1016/j.cell.2007.07.025. View

10.

Chappard D, Guillaume B, Mallet R, Pascaretti-Grizon F, Basle M, Libouban H . Sinus lift augmentation and beta-TCP: a microCT and histologic analysis on human bone biopsies. Micron. 2010; 41(4):321-6. DOI: 10.1016/j.micron.2009.12.005. View

11.

Weinbaum S, Cowin S, Zeng Y . A model for the excitation of osteocytes by mechanical loading-induced bone fluid shear stresses. J Biomech. 1994; 27(3):339-60. DOI: 10.1016/0021-9290(94)90010-8. View

12.

Celil Aydemir A, Minematsu H, Gardner T, Kim K, Ahn J, Young-In Lee F . Nuclear factor of activated T cells mediates fluid shear stress- and tensile strain-induced Cox2 in human and murine bone cells. Bone. 2009; 46(1):167-75. PMC: 2818272. DOI: 10.1016/j.bone.2009.08.061. View

13.

Schneider R, Puellen A, Kramann R, Raupach K, Bornemann J, Knuechel R . The osteogenic differentiation of adult bone marrow and perinatal umbilical mesenchymal stem cells and matrix remodelling in three-dimensional collagen scaffolds. Biomaterials. 2009; 31(3):467-80. DOI: 10.1016/j.biomaterials.2009.09.059. View

14.

Gersbach C, Phillips J, Garcia A . Genetic engineering for skeletal regenerative medicine. Annu Rev Biomed Eng. 2007; 9:87-119. DOI: 10.1146/annurev.bioeng.9.060906.151949. View

15.

Rho J, Zioupos P . Mechanical properties and the hierarchical structure of bone. Med Eng Phys. 1998; 20(2):92-102. DOI: 10.1016/s1350-4533(98)00007-1. View

16.

Vukicevic S, Grgurevic L . BMP-6 and mesenchymal stem cell differentiation. Cytokine Growth Factor Rev. 2009; 20(5-6):441-8. DOI: 10.1016/j.cytogfr.2009.10.020. View

17.

Urist M . Bone: formation by autoinduction. Science. 1965; 150(3698):893-9. DOI: 10.1126/science.150.3698.893. View

18.

Rodan G, Martin T . Therapeutic approaches to bone diseases. Science. 2000; 289(5484):1508-14. DOI: 10.1126/science.289.5484.1508. View

19.

Laurencin C, Ambrosio A, Borden M, Cooper Jr J . Tissue engineering: orthopedic applications. Annu Rev Biomed Eng. 2001; 1:19-46. DOI: 10.1146/annurev.bioeng.1.1.19. View

20.

Kong H, Liu J, Riddle K, Matsumoto T, Leach K, Mooney D . Non-viral gene delivery regulated by stiffness of cell adhesion substrates. Nat Mater. 2005; 4(6):460-4. DOI: 10.1038/nmat1392. View