The Infant Microbiome Development: Mom Matters

Overview

Journal Trends Mol Med

Specialties General Medicine
Molecular Biology

Date 2015 Jan 13

PMID 25578246

Citations 394

Authors

Noel T Mueller

Elizabeth Bakacs

Joan Combellick

Zoya Grigoryan

Maria G Dominguez-Bello

Affiliations

Soon will be listed here.

Abstract

The infant microbiome plays an essential role in human health and its assembly is determined by maternal-offspring exchanges of microbiota. This process is affected by several practices, including Cesarean section (C-section), perinatal antibiotics, and formula feeding, that have been linked to increased risks of metabolic and immune diseases. Here we review recent knowledge about the impacts on infant microbiome assembly, discuss preventive and restorative strategies to ameliorate the effects of these impacts, and highlight where research is needed to advance this field and improve the health of future generations.

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